Language:

Aquaporins in health and disease

Molecular Medicine Today, 2000-02, Vol.6 (2), p.60-65 [Peer Reviewed Journal]

2000 Elsevier Science Ltd ;ISSN: 1357-4310 ;DOI: 10.1016/S1357-4310(99)01636-6 ;PMID: 10652478

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Aquaporins in health and disease
Author: King, Landon S ; Yasui, Masato ; Agre, Peter
Subjects: Animals ; Aquaporins - chemistry ; Aquaporins - genetics ; Aquaporins - metabolism ; Brain - metabolism ; Diabetes ; Disease ; Edema ; Erythrocytes - metabolism ; Erythrocytes - pathology ; Eye - metabolism ; Eye - physiopathology ; Homeostasis ; Humans ; Insipidus ; Kidney ; Kidney - metabolism ; Kidney - physiopathology ; Lung ; Membrane protein ; Permeability ; Respiratory System - metabolism ; Salivary Glands - metabolism ; Salivary Glands - physiopathology ; Water ; Water - metabolism
Is Part Of: Molecular Medicine Today, 2000-02, Vol.6 (2), p.60-65
Description: The molecular basis of membrane water-permeability remained elusive until the recent discovery of the aquaporin water-channel proteins. The fundamental importance of these proteins is suggested by their conservation from bacteria through plants to mammals. Ten mammalian aquaporins have thus far been identified, each with a distinct distribution. In the kidney, lung, eye and brain, multiple water-channel homologs are expressed, providing a network for water transport in those locations. It is increasingly clear that alterations in aquaporin expression or function can be rate-limiting for water transport across certain membranes. Aquaporins are likely to prove central to the pathophysiology of a variety of clinical conditions from diabetes insipidus to various forms of edema and, ultimately, they could be a target for therapy in diseases of altered water homeostasis.
Publisher: England: Elsevier B.V
Language: English
Identifier: ISSN: 1357-4310
DOI: 10.1016/S1357-4310(99)01636-6
PMID: 10652478
Source: MEDLINE
Alma/SFX Local Collection

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Aquaporins in health and disease

2000 Elsevier Science Ltd ;ISSN: 1357-4310 ;DOI: 10.1016/S1357-4310(99)01636-6 ;PMID: 10652478

Searching Remote Databases, Please Wait