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Vitamin D Deficiency and Antenatal and Postpartum Depression: A Systematic Review

Nutrients, 2018-04, Vol.10 (4), p.478 [Peer Reviewed Journal]

Copyright MDPI AG 2018 ;2018 by the authors. 2018 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu10040478 ;PMID: 29649128

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Title:
Vitamin D Deficiency and Antenatal and Postpartum Depression: A Systematic Review
Author: Aghajafari, Fariba ; Letourneau, Nicole ; Mahinpey, Newsha ; Cosic, Nela ; Giesbrecht, Gerald
Subjects: 25(OH)D ; Adult ; Affect ; antenatal depression ; Biomarkers - blood ; depression ; Depression, Postpartum - diagnosis ; Depression, Postpartum - epidemiology ; Depression, Postpartum - psychology ; Female ; Humans ; Maternal Nutritional Physiological Phenomena ; Mental depression ; Nitric-oxide synthase ; Nutrient deficiency ; Nutritional Status ; Odds Ratio ; postnatal depression ; Postpartum ; Postpartum depression ; Pregnancy ; Prenatal depression ; Quality assessment ; Quality control ; Review ; Reviews ; Risk Factors ; Statistical analysis ; Systematic review ; Vitamin D ; Vitamin D - analogs & derivatives ; Vitamin D - blood ; Vitamin D Deficiency - blood ; Vitamin D Deficiency - diagnosis ; Vitamin D Deficiency - epidemiology ; Vitamin deficiency ; Young Adult
Is Part Of: Nutrients, 2018-04, Vol.10 (4), p.478
Description: Vitamin D has been implicated in antenatal depression (AD) and postpartum depression (PPD) in many studies; however, results have been inconsistent due to the complexity of this association. We searched the MEDLINE, Embase, PsycINFO, and Maternity and Infant Care databases for literature addressing associations between vitamin D and AD and PPD. Two independent authors reviewed titles and abstracts of the search results and selected studies for full review. Data were extracted, and a quality rating was done using the Newcastle-Ottawa Scale (NOS) on the selected studies. A total of 239 studies were identified; 14 were included in the review. The quality assessment of the included studies ranged from moderate to high. Of the studies on PPD, five of nine (55%) showed a significant association between vitamin D and PPD. Five of seven (71%) studies on AD showed a significant association with vitamin D status. As the included studies used different effect estimates and statistical analyses to report the association, it was not possible to transform the existing data into one single effect measure to employ meta-analytic techniques. While results of this systematic review vary, they indicate a significant association between vitamin D status and AD and PD.
Publisher: Switzerland: MDPI AG
Language: English
Identifier: ISSN: 2072-6643
EISSN: 2072-6643
DOI: 10.3390/nu10040478
PMID: 29649128
Source: GFMER Free Medical Journals
MEDLINE
PubMed Central
ROAD: Directory of Open Access Scholarly Resources
ProQuest Central
DOAJ Directory of Open Access Journals

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Vitamin D Deficiency and Antenatal and Postpartum Depression: A Systematic Review

Copyright MDPI AG 2018 ;2018 by the authors. 2018 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu10040478 ;PMID: 29649128

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