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Perindopril - značajan doprinos liječenju arterijske hipertenzije i kardiovaskularnih bolesti

Cardiologia Croatica, 2011-03, Vol.6 (3-4), p.56

ISSN: 1848-543X ;EISSN: 1848-5448

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  • Title:
    Perindopril - značajan doprinos liječenju arterijske hipertenzije i kardiovaskularnih bolesti
  • Author: Barbič-Žagar, Breda ; Grošelj, Mateja ; Milovanovič Jarh, Darja
  • Subjects: arterijska hipertenzija ; cardiovascular disease ; efficacy ; hypertension ; kardiovaskularne bolesti ; perindopril ; safety ; sigurnost ; učinkovitost
  • Is Part Of: Cardiologia Croatica, 2011-03, Vol.6 (3-4), p.56
  • Description: Hypertension is a major cardiovascular and cerebrovascular risk factor and is highly prevalent throughout the world, affecting 50% of people over 60 years of age. Angiotensin-converting enzyme (ACE) inhibitors are the gold standard in the treatment of hypertension. However, there exist important differences among the available ACE inhibitors. Perindopril is distinguished based on specific characteristics, such as long duration of action, 24-hour blood pressure control, high lipophilicity, and high tissue ACE affinity. Moreover, clinical studies investigating the effects of perindopril on morbidity and mortality have provided evidence of its benefits along cardiovascular disease continuum. Since inappropriate treatment was one of the most important reasons for the inadequate blood pressure control, the high efficacy and safety of Perineva® (Krka’s perindopril) and its availability in a variety of dosage forms, strengths and fixed-dose combinations might facilitate the management of hypertension and improve compliance among the Croatian patients
  • Publisher: Hrvatsko kardiološko društvo
  • Language: Croatian;English
  • Identifier: ISSN: 1848-543X
    EISSN: 1848-5448
  • Source: GFMER Free Medical Journals
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