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Postsurgical Cystoid Macular Edema

Developments in ophthalmology, 2017, Vol.58, p.178-190 [Peer Reviewed Journal]

2017 S. Karger AG, Basel ;2017 S. Karger AG, Basel. ;ISSN: 0250-3751 ;ISBN: 9783318060324 ;ISBN: 3318060321 ;EISSN: 1662-2790 ;EISBN: 9783318060331 ;EISBN: 331806033X ;DOI: 10.1159/000455280 ;OCLC: 982012665 ;PMID: 28351047 ;LCCallNum: RE661.M3.M338 2017

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  • Title:
    Postsurgical Cystoid Macular Edema
  • Author: Zur, Dinah ; Loewenstein, Anat
  • Coscas, G ; Loewenstein, A ; Cunha-Vaz, J ; Soubrane, G
  • Subjects: Anti-Inflammatory Agents - therapeutic use ; Cataract Extraction - adverse effects ; Chapter ; Fluorescein Angiography - methods ; Fundus Oculi ; Humans ; Macular Edema - diagnosis ; Macular Edema - etiology ; Macular Edema - therapy ; Ophthalmology ; Postoperative Complications ; Tomography, Optical Coherence - methods ; Vitreoretinal Surgery - adverse effects
  • Is Part Of: Developments in ophthalmology, 2017, Vol.58, p.178-190
  • Description: Cystoid macular edema (CME) is a primary cause of reduced vision following both cataract and successful vitreoretinal surgery. The incidence of clinical CME following modern cataract surgery is 0.1-2.35%. Preexisting conditions such as diabetes mellitus and uveitis as well as intraoperative complications can raise the risk of postsurgical CME. The etiology of CME is not completely understood. Prolapsed or incarcerated vitreous and postoperative inflammatory processes have been proposed as causative agents. Pseudophakic CME is characterized by poor postoperative visual acuity. Fluorescein angiography shows the classical perifoveal petaloid staining pattern and late leakage of the optic disk. Optical coherence tomography is a useful diagnostic tool, which displays cystic spaces in the outer nuclear layer. The most important differential diagnoses include age-related macular degeneration and other causes of CME such as diabetic macular edema. Most cases of pseudophakic CME resolve spontaneously. The value of prophylactic treatment is doubtful. First-line treatment of postsurgical CME should include topical nonsteroidal anti-inflammatory drugs and corticosteroids. Oral carbonic anhydrase inhibitors can be considered complementary. In cases of resistant CME, periocular or intraocular corticosteroids present an option. Antiangiogenic agents, though experimental, should be considered for nonresponsive persistent CME. Surgical options should be reserved for special indications.
  • Publisher: Basel, Switzerland: S. Karger AG
  • Language: English
  • Identifier: ISSN: 0250-3751
    ISBN: 9783318060324
    ISBN: 3318060321
    EISSN: 1662-2790
    EISBN: 9783318060331
    EISBN: 331806033X
    DOI: 10.1159/000455280
    OCLC: 982012665
    PMID: 28351047
    LCCallNum: RE661.M3.M338 2017
  • Source: MEDLINE
    Alma/SFX Local Collection
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