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Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

Nature reviews. Immunology, 2021-10, Vol.21 (10), p.626-636 [Peer Reviewed Journal]

2021. Springer Nature Limited. ;COPYRIGHT 2021 Nature Publishing Group ;Springer Nature Limited 2021. ;Springer Nature Limited 2021 ;ISSN: 1474-1733 ;EISSN: 1474-1741 ;DOI: 10.1038/s41577-021-00592-1 ;PMID: 34373623

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Title:
Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape
Author: Tregoning, John S ; Flight, Katie E ; Higham, Sophie L ; Wang, Ziyin ; Pierce, Benjamin F
Subjects: Adverse and side effects ; Clinical Trials as Topic ; Control ; Coronaviruses ; COVID-19 ; COVID-19 vaccines ; COVID-19 Vaccines - administration & dosage ; COVID-19 Vaccines - adverse effects ; COVID-19 Vaccines - classification ; COVID-19 Vaccines - immunology ; Drugs ; Epidemics ; Health Services Accessibility ; Humans ; Medical research ; Medicine, Experimental ; Pandemics ; Progress ; SARS-CoV-2 - classification ; SARS-CoV-2 - genetics ; SARS-CoV-2 - immunology ; Severe acute respiratory syndrome coronavirus 2 ; United Kingdom ; Vaccine efficacy ; Vaccines ; Viruses ; World Health Organization
Is Part Of: Nature reviews. Immunology, 2021-10, Vol.21 (10), p.626-636
Description: Where 2020 saw the development and testing of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has seen vaccine rollout in many countries. In this Progress article, we provide a snapshot of ongoing vaccine efficacy studies, as well as real-world data on vaccine effectiveness and the impact of virus variants of concern. Where they have been deployed in a high proportion of the adult population, the currently approved vaccines have been extremely effective in preventing COVID-19, particularly severe disease. Nonetheless, there are still significant challenges in ensuring equitable vaccine access around the globe and lessons that can be learned for controlling this pandemic and for the next pandemic.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 1474-1733
EISSN: 1474-1741
DOI: 10.1038/s41577-021-00592-1
PMID: 34373623
Source: MEDLINE
ProQuest Central

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Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

2021. Springer Nature Limited. ;COPYRIGHT 2021 Nature Publishing Group ;Springer Nature Limited 2021. ;Springer Nature Limited 2021 ;ISSN: 1474-1733 ;EISSN: 1474-1741 ;DOI: 10.1038/s41577-021-00592-1 ;PMID: 34373623

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