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A journey into a Mediterranean diet and type 2 diabetes: a systematic review with meta-analyses

BMJ open, 2015-08, Vol.5 (8), p.e008222-e008222 [Peer Reviewed Journal]

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions ;Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. ;Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions 2015 This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions 2015 ;ISSN: 2044-6055 ;EISSN: 2044-6055 ;DOI: 10.1136/bmjopen-2015-008222 ;PMID: 26260349

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  • Title:
    A journey into a Mediterranean diet and type 2 diabetes: a systematic review with meta-analyses
  • Author: Esposito, Katherine ; Maiorino, Maria Ida ; Bellastella, Giuseppe ; Chiodini, Paolo ; Panagiotakos, Demosthenes ; Giugliano, Dario
  • Subjects: Adult ; Blood Glucose - analysis ; Cardiovascular Diseases - epidemiology ; Cholesterol, HDL - blood ; Diabetes and Endocrinology ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - diet therapy ; Diabetes Mellitus, Type 2 - prevention & control ; Diet, Fat-Restricted ; Diet, Mediterranean ; Humans ; Randomized Controlled Trials as Topic ; Risk Factors ; Systematic review ; Weight Loss
  • Is Part Of: BMJ open, 2015-08, Vol.5 (8), p.e008222-e008222
  • Description: ObjectivesTo summarise the evidence about the efficacy of a Mediterranean diet on the management of type 2 diabetes and prediabetic states.DesignA systematic review of all meta-analyses and randomised controlled trials (RCTs) that compared the Mediterranean diet with a control diet on the treatment of type 2 diabetes and prediabetic states was conducted. Electronic searches were carried out up to January 2015. Trials were included for meta-analyses if they had a control group treated with another diet, if they were of sufficient duration (at least 6 months), and if they had at least 30 participants in each arm. A random-effect model was used to pool data.ParticipantsAdults with or at risk for type 2 diabetes.InterventionsDietary patterns that described themselves as using a ‘Mediterranean’ dietary pattern.Outcome measuresThe outcomes were glycaemic control, cardiovascular risk factors and remission from the metabolic syndrome.ResultsFrom 2824 studies, 8 meta-analyses and 5 RCTs were eligible. A ‘de novo’ meta-analysis of 3 long-term (>6 months) RCTs of the Mediterranean diet and glycaemic control of diabetes favoured the Mediterranean diet as compared with lower fat diets. Another ‘de novo’ meta-analysis of two long-term RCTs showed a 49% increased probability of remission from the metabolic syndrome. 5 meta-analyses showed a favourable effect of the Mediterranean diet, as compared with other diets, on body weight, total cholesterol and high-density lipoprotein cholesterol. 2 meta-analyses demonstrated that higher adherence to the Mediterranean diet reduced the risk of future diabetes by 19–23%.ConclusionsThe Mediterranean diet was associated with better glycaemic control and cardiovascular risk factors than control diets, including a lower fat diet, suggesting that it is suitable for the overall management of type 2 diabetes.
  • Publisher: England: BMJ Publishing Group LTD
  • Language: English
  • Identifier: ISSN: 2044-6055
    EISSN: 2044-6055
    DOI: 10.1136/bmjopen-2015-008222
    PMID: 26260349
  • Source: ProQuest One Psychology
    BMJ Open Access Journals
    Geneva Foundation Free Medical Journals at publisher websites
    MEDLINE
    PubMed Central
    ROAD: Directory of Open Access Scholarly Resources
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