Language:

Presentation and Outcomes of Patients with ESKD and COVID-19

Journal of the American Society of Nephrology, 2020-07, Vol.31 (7), p.1409-1415 [Peer Reviewed Journal]

Copyright © 2020 by the American Society of Nephrology. ;Copyright © 2020 by the American Society of Nephrology 2020 ;ISSN: 1046-6673 ;EISSN: 1533-3450 ;DOI: 10.1681/ASN.2020040470 ;PMID: 32467113

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Presentation and Outcomes of Patients with ESKD and COVID-19
Author: Valeri, Anthony M ; Robbins-Juarez, Shelief Y ; Stevens, Jacob S ; Ahn, Wooin ; Rao, Maya K ; Radhakrishnan, Jai ; Gharavi, Ali G ; Mohan, Sumit ; Husain, S Ali
Subjects: Adult ; Age Factors ; Aged ; Cause of Death ; Cohort Studies ; Comorbidity ; Coronavirus Infections - diagnosis ; Coronavirus Infections - epidemiology ; Coronavirus Infections - therapy ; COVID-19 ; Female ; Hospital Mortality - trends ; Hospitalization - statistics & numerical data ; Hospitals, University ; Humans ; Infection Control - organization & administration ; Intensive Care Units - organization & administration ; Kidney Failure, Chronic - diagnosis ; Kidney Failure, Chronic - epidemiology ; Kidney Failure, Chronic - therapy ; Male ; Middle Aged ; New York City ; Outcome Assessment, Health Care ; Pandemics ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - epidemiology ; Pneumonia, Viral - therapy ; Prevalence ; Rapid Communication ; Renal Dialysis - methods ; Renal Dialysis - mortality ; Retrospective Studies ; Risk Assessment ; Severity of Illness Index ; Sex Factors ; Statistics, Nonparametric ; Survival Analysis ; Vulnerable Populations - statistics & numerical data
Is Part Of: Journal of the American Society of Nephrology, 2020-07, Vol.31 (7), p.1409-1415
Description: The relative immunosuppression and high prevalence of comorbidities in patients with ESKD on dialysis raise concerns that they may have an elevated risk of severe coronavirus disease 2019 (COVID-19), but outcomes for COVID-19 in such patients are unclear. To examine presentation and outcomes of COVID-19 in patients with ESKD on dialysis, we retrospectively collected clinical data on 59 patients on dialysis who were hospitalized with COVID-19. We used Wilcoxon rank sum and Fischer exact tests to compare patients who died versus those still living. Two of the study's 59 patients were on peritoneal dialysis, and 57 were on hemodialysis. Median age was 63 years, with high prevalence of hypertension (98%) and diabetes (69%). Patients who died were significantly older than those still living (median age, 75 versus 62 years) and had a higher median Charlson comorbidity index (8 versus 7). The most common presenting symptoms were fever (49%) and cough (39%); initial radiographs most commonly showed multifocal or bilateral opacities (59%). By end of follow-up, 18 patients (31%) died a median 6 days after hospitalization, including 75% of patients who required mechanical ventilation. Eleven of those who died had advanced directives against intubation. The remaining 41 patients (69%) were discharged home a median 8 days after admission. The median initial white blood cell count was significantly higher in patients who died compared with those still living (7.5 versus 5.7×10 / l), as was C-reactive protein (163 versus 80 mg/L). The association of COVID-19 with high mortality in patients with ESKD on dialysis reinforces the need to take appropriate infection control measures to prevent COVID-19 spread in this vulnerable population.
Publisher: United States: American Society of Nephrology
Language: English
Identifier: ISSN: 1046-6673
EISSN: 1533-3450
DOI: 10.1681/ASN.2020040470
PMID: 32467113
Source: Open Access: PubMed Central
Geneva Foundation Free Medical Journals at publisher websites
MEDLINE
Alma/SFX Local Collection

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Presentation and Outcomes of Patients with ESKD and COVID-19

Copyright © 2020 by the American Society of Nephrology. ;Copyright © 2020 by the American Society of Nephrology 2020 ;ISSN: 1046-6673 ;EISSN: 1533-3450 ;DOI: 10.1681/ASN.2020040470 ;PMID: 32467113

Searching Remote Databases, Please Wait