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Choline concentration in normal blood donor and cardiac troponin-positive plasma samples

Clinical chemistry (Baltimore, Md.), 2006-11, Vol.52 (11), p.2123-2124 [Peer Reviewed Journal]

COPYRIGHT 2006 American Association for Clinical Chemistry, Inc. ;Copyright American Association for Clinical Chemistry Nov 2006 ;ISSN: 0009-9147 ;EISSN: 1530-8561 ;DOI: 10.1373/clinchem.2006.074369 ;PMID: 17068179

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Title:
Choline concentration in normal blood donor and cardiac troponin-positive plasma samples
Author: Adamczyk, Maciej ; Brashear, R Jeffrey ; Mattingly, Phillip G
Subjects: Acute coronary syndromes ; Analysis ; Apoptosis ; Biomarkers - blood ; Blood & organ donations ; Blood Donors ; Blood lipids ; Cardiology ; Choline ; Choline - blood ; Clinical Chemistry Tests - economics ; Heart attacks ; Humans ; Mass spectrometry ; Medical research ; Medicine, Experimental ; Myocardial Ischemia - blood ; Myocardial Ischemia - diagnosis ; Plasma ; Predictive Value of Tests ; Reference Values ; Time Factors ; Troponin I - blood
Is Part Of: Clinical chemistry (Baltimore, Md.), 2006-11, Vol.52 (11), p.2123-2124
Description: (3) used analysis of choline in whole blood by liquid chromatography-mass spectrometry to perform a prospective study of cardiac troponin-negative patients with suspected acute coronary syndrome and concluded that increased whole-blood choline concentrations were predictive of cardiac death and nontatal cardiac arrest. Increased cardiac troponin-I is indicative of myocardial cell death attributable to prolonged ischemia and is used in the diagnosis of acute myocardial infarction; however, this biomarker can be increased in other conditions such as myocarditis (7) or myocardial ischemia-reperfusion injury (8,9).
Publisher: England: American Association for Clinical Chemistry, Inc
Language: English
Identifier: ISSN: 0009-9147
EISSN: 1530-8561
DOI: 10.1373/clinchem.2006.074369
PMID: 17068179
Source: MEDLINE
ProQuest Central

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Choline concentration in normal blood donor and cardiac troponin-positive plasma samples

COPYRIGHT 2006 American Association for Clinical Chemistry, Inc. ;Copyright American Association for Clinical Chemistry Nov 2006 ;ISSN: 0009-9147 ;EISSN: 1530-8561 ;DOI: 10.1373/clinchem.2006.074369 ;PMID: 17068179

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