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Quantitation of glutamate mGluR5 receptor with 18F-FPEB PET in humans

NeuroImage (Orlando, Fla.), 2010-08, Vol.52 (S1), p.S202-S202 [Peer Reviewed Journal]

2010 ;Copyright Elsevier Limited Aug 1, 2010 ;ISSN: 1053-8119 ;EISSN: 1095-9572 ;DOI: 10.1016/j.neuroimage.2010.04.164

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  • Title:
    Quantitation of glutamate mGluR5 receptor with 18F-FPEB PET in humans
  • Author: Barret, Olivier ; Tamagnan, Gilles ; Batis, Jeff ; Jennings, Danna ; Zubal, Georges ; Russel, David ; Marek, Ken ; Seiby, John
  • Subjects: Estimates
  • Is Part Of: NeuroImage (Orlando, Fla.), 2010-08, Vol.52 (S1), p.S202-S202
  • Description: The purpose of this study is to characterize 18F-FPEB, a novel mGluR5 tracer in humans, and evaluate simple tissue ratio against different non invasive kinetic models using the cerebellum as reference region, where there is very low levels of mGluR5 levels in humans. 12 subjects (4 Healthy Controls, 6 Parkinson's Disease and 2 Huntington's Disease) were imaged with 18F-FPEB PET over 4.5h.
  • Publisher: Amsterdam: Elsevier Inc
  • Language: English
  • Identifier: ISSN: 1053-8119
    EISSN: 1095-9572
    DOI: 10.1016/j.neuroimage.2010.04.164
  • Source: ProQuest One Psychology
    AUTh Library subscriptions: ProQuest Central
    Alma/SFX Local Collection
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