skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Aflibercept versus dexamethasone for macular edema secondary to central retinal vein occlusion

Medwave, 2019-12, Vol.19 (11), p.e7739-e7738

ISSN: 0717-6384 ;EISSN: 0717-6384 ;DOI: 10.5867/medwave.2019.11.7738 ;PMID: 31891353

Full text available

Citations Cited by
  • Title:
    Aflibercept versus dexamethasone for macular edema secondary to central retinal vein occlusion
  • Author: Garretón, Rodolfo ; Gonzalez, Raul
  • Subjects: aflibercept ; dexamethasone ; epistemonikos ; grade ; macular edema
  • Is Part Of: Medwave, 2019-12, Vol.19 (11), p.e7739-e7738
  • Description: Macular edema is a frequent complication of central retinal vein occlusion that might lead to deterioration of visual acuity. The most commonly used treatments are dexamethasone implant and anti-vascular endothelial growth factor drugs, being aflibercept one of the most commonly used them. However, there is no consensus about which treatment constitute the best alternative. We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach. We identified two systematic reviews that included four primary studies overall, all randomized trials. We concluded that it is not possible to establish whether aflibercept is superior to dexamethasone in terms of improvement of visual acuity and safety, because the certainty of the existing evidence has been evaluated as very low.
  • Publisher: Chile: Medwave Estudios Limitada
  • Language: Spanish;English
  • Identifier: ISSN: 0717-6384
    EISSN: 0717-6384
    DOI: 10.5867/medwave.2019.11.7738
    PMID: 31891353
  • Source: DOAJ Directory of Open Access Journals
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait