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Regiodivergent Synthesis of 11H-Indolo[3,2-c]quinolines and Neocryptolepine from a Common Starting Material

Navngivelse 4.0 Internasjonal The authors ;ISSN: 1434-193X ;EISSN: 1099-0690 ;DOI: 10.1002/ejoc.202300137

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  • Title:
    Regiodivergent Synthesis of 11H-Indolo[3,2-c]quinolines and Neocryptolepine from a Common Starting Material
  • Author: Håheim, Katja Stangeland ; Lund, Bjarte Aarmo ; Sydnes, Magne Olav
  • Subjects: Kjemi ; Matematikk og Naturvitenskap
  • Description: A large number of diversely functionalized analogs of the bioactive natural products neocryptolepine and isocryptolepine have been prepared from a series of 3-bromoquinoline derivatives. The neocryptolepines were obtained by a Pd0-catalyzed C−C bond coupling followed by C−N bond formation in yields up to 80 %, whereas the indoloquinolines were prepared by a Suzuki-Miyaura cross-coupling followed by azidation-photochemical cyclization in yields ranging from traces to 95 % yield. publishedVersion
  • Publisher: Chemistry Europe
  • Creation Date: 2023
  • Language: English
  • Identifier: ISSN: 1434-193X
    EISSN: 1099-0690
    DOI: 10.1002/ejoc.202300137
  • Source: Brage Consortium Repository
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