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Cardiovascular prevention: lifestyle and statins--competitors or companions?

SAMJ: South African Medical Journal, 2014-03, Vol.104 (3), p.168-173 [Peer Reviewed Journal]

COPYRIGHT 2014 Health & Medical Publishing Group ;COPYRIGHT 2014 Health & Medical Publishing Group ;This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 International License. ;ISSN: 0256-9574 ;ISSN: 2078-5135 ;EISSN: 2078-5135 ;DOI: 10.7196/SAMJ.7942 ;PMID: 24897816

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Title:
Cardiovascular prevention: lifestyle and statins--competitors or companions?
Author: Opie, L H ; Dalby, A J
Subjects: Cardiovascular diseases ; Cardiovascular Diseases - prevention & control ; Diet ; Dosage and administration ; Exercise ; Health aspects ; Health Care Sciences & Services ; Health Policy & Services ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use ; Life Style ; Medical Ethics ; Medicine, General & Internal ; Medicine, Legal ; Medicine, Research & Experimental ; Prevention ; Social aspects ; Statins
Is Part Of: SAMJ: South African Medical Journal, 2014-03, Vol.104 (3), p.168-173
Description: Favourable lifestyles promote cardiovascular protection. Exercise can induce beneficial changes in the genome that decrease low-density lipoprotein cholesterol (LDL-C) and increase anti-inflammatory markers. The Mediterranean dietary pattern, fortified by nuts, while not reducing weight, reduces mortality. Lifestyle changes combined with statin therapy provide potent protection against coronary heart disease, especially when used for secondary prevention after cardiovascular events. Decisions regarding the initiation of statin therapy for primary prevention are more difficult, requiring consideration of both the LDL-C level and the degree of cardiovascular risk for dyslipidaemic patients. Combining intensive exercise and statin therapy substantially reduces the mortality risk, and thus is potentially the ideal risk-reducing combination.
Publisher: South Africa: Health & Medical Publishing Group
Language: English;Portuguese
Identifier: ISSN: 0256-9574
ISSN: 2078-5135
EISSN: 2078-5135
DOI: 10.7196/SAMJ.7942
PMID: 24897816
Source: SciELO
African Journals Online (Open Access)
GFMER Free Medical Journals
MEDLINE
Alma/SFX Local Collection
DOAJ Directory of Open Access Journals

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Cardiovascular prevention: lifestyle and statins--competitors or companions?

COPYRIGHT 2014 Health & Medical Publishing Group ;COPYRIGHT 2014 Health & Medical Publishing Group ;This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 International License. ;ISSN: 0256-9574 ;ISSN: 2078-5135 ;EISSN: 2078-5135 ;DOI: 10.7196/SAMJ.7942 ;PMID: 24897816

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