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Dry Eye and Meibomian Glands in Vitiligo

Turk oftalmoloji gazetesi, 2021-04, Vol.51 (2), p.70-74 [Peer Reviewed Journal]

COPYRIGHT 2021 Galenos Yayinevi Tic. Ltd. ;2021. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Copyright 2021 by Turkish Ophthalmological Association | Turkish Journal of Ophthalmology, published by Galenos Publishing House. 2021 ;ISSN: 1300-0659 ;ISSN: 2149-8695 ;EISSN: 2149-8709 ;EISSN: 2147-2661 ;DOI: 10.4274/tjo.galenos.2020.78027 ;PMID: 33951893

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Title:
Dry Eye and Meibomian Glands in Vitiligo
Author: Taheri, Ahmad Reza ; Allahyari, Elahe ; Rudi, Borhan Haghi ; Nikandish, Malihe
İrkeç,Murat
Subjects: Adult ; Case-Control Studies ; dry eye ; Dry Eye Syndromes - diagnosis ; Dry Eye Syndromes - epidemiology ; Dry Eye Syndromes - etiology ; Eye ; Eye diseases ; Female ; Humans ; Incidence ; Iran - epidemiology ; Male ; Medical examination ; meibomian glands ; Meibomian Glands - diagnostic imaging ; Meibomian Glands - metabolism ; Original ; Pathogenesis ; Questionnaires ; Skin ; Skin diseases ; Slit Lamp Microscopy ; Tears - metabolism ; Tıp ; Vitiligo ; Vitiligo - complications ; Vitiligo - metabolism
Is Part Of: Turk oftalmoloji gazetesi, 2021-04, Vol.51 (2), p.70-74
Description: To evaluate aqueous and lipid tear film parameters and the meibomian glands (MGs) with non-contact meibography in patients with vitiligo. This case-control study was conducted in the right (OD) and left (OS) eyes of 43 patients with vitiligo and 43 controls in Birjand, Iran. In addition to demographic information and skin disease characteristics, the Ocular Surface Disease Index (OSDI) questionnaire was completed for each patient, followed by eye examinations including slit lamp examination, Schirmer test, strip meniscometry (SMTube), and tear break-up time (TBUT) measurement. The MGs were also imaged using a non-contact meibography system (SBM System, Italy). The data were analyzed using SPSS version 22.0 with a significant level of less than 0.05. Patients had higher OSDI score than controls but it was not significant (10.90±13.03 vs. 5.57±6.85; p=0.07). There were significant differences between the groups in mean Schirmer test values for both eyes (OD: 8.07±5.47 vs. 17.37±6.52; OS: 7.60±5.00 vs. 17.30±6.44, p<0.001) and mean SMTube results (OD: 4.49±2.40 vs. 9.74±3.67; OS: 4.30±2.81 vs. 9.65±4.52; p<0.001). However, mean TBUT did not differ between the groups (OD: 9.14±3.17 vs. 10.12±2.08, p=0.27; OS: 9.16±3.30 vs. 10.05±2.10, p=0.25). Meibography also showed no significant difference in MG dropout between the groups (OD: 20.86±9.79 vs. 21.05±12.07; p=0.74; OS: 18.16±8.83 vs. 19.53±10.30; p=0.51). Vitiligo is associated with a reduction in the production of aqueous tear film, but does not affect the structure and function of the MGs.
Publisher: Turkey: Galenos Yayinevi Tic. Ltd
Language: English;Turkish
Identifier: ISSN: 1300-0659
ISSN: 2149-8695
EISSN: 2149-8709
EISSN: 2147-2661
DOI: 10.4274/tjo.galenos.2020.78027
PMID: 33951893
Source: AUTh Library subscriptions: ProQuest Central
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Dry Eye and Meibomian Glands in Vitiligo

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