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0.5 gigapixel microscopy using a flatbed scanner

Biomedical optics express, 2013-12, Vol.5 (1), p.1-8 [Peer Reviewed Journal]

2013 Optical Society of America 2013 Optical Society of America ;ISSN: 2156-7085 ;EISSN: 2156-7085 ;DOI: 10.1364/BOE.5.000001 ;PMID: 24466471

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  • Title:
    0.5 gigapixel microscopy using a flatbed scanner
  • Author: Zheng, Guoan ; Ou, Xiaoze ; Yang, Changhuei
  • Subjects: Microscopy
  • Is Part Of: Biomedical optics express, 2013-12, Vol.5 (1), p.1-8
  • Description: The capability to perform high-resolution, wide field-of-view (FOV) microscopy imaging is highly sought after in biomedical applications. In this paper, we report a wide FOV microscopy system that uses a closed-circuit-television (CCTV) lens for image relay and a flatbed scanner for data acquisition. We show that such an imaging system is capable of capturing a 10 mm × 7.5 mm FOV image with 0.78 µm resolution, resulting in more than 0.5 billion pixels across the entire image. The resolution and field curve of the proposed system were characterized by imaging a USAF resolution target and a hole-array target. To demonstrate its application, 0.5 gigapixel images of histology slides were acquired using this system.
  • Publisher: United States: Optical Society of America
  • Language: English
  • Identifier: ISSN: 2156-7085
    EISSN: 2156-7085
    DOI: 10.1364/BOE.5.000001
    PMID: 24466471
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    PubMed Central
    ROAD: Directory of Open Access Scholarly Resources
    DOAJ Directory of Open Access Journals
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