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Clinical Symptoms and Management of Beta Thalassemia

Indian journal of clinical biochemistry, 2022-05, Vol.32 (S1), p.S75 [Peer Reviewed Journal]

COPYRIGHT 2022 Springer ;ISSN: 0970-1915 ;EISSN: 0974-0422

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  • Title:
    Clinical Symptoms and Management of Beta Thalassemia
  • Author: Nigam, Nitu ; Agarwal, Monica ; Singh, Prithvi Kumar ; Hussain, Syed Rizwan
  • Subjects: Developing countries ; Thalassemia
  • Is Part Of: Indian journal of clinical biochemistry, 2022-05, Vol.32 (S1), p.S75
  • Description: Thalassemia is a single gene disorder is characterised by reduction or absence of beta-globin chain. It is commomest in the Middle East, Southeast Asia, African and some Asian countries including India. Thalassemia has diverse clinical phenotypes. Thalassemia major patients present with severe anemia requiring regular blood transfusion for survival whereas Thalassemia trait is characterized by mild hypochromic, microcytic anemia with elevated HbA2 levels. The prevalence of thalassemia in India 3.3% and a high of 17% in certain communities. There are 30 million carriers and approximately 10000 children are born with the disease every year. Estimated cost for treatment is 1 lacs per child per year which is difficult to afford in developing countries. Management of thalassemics is not only traumatic to the family but also poses a tremendous socioeconomic burden on the country making.
  • Publisher: Springer
  • Language: English
  • Identifier: ISSN: 0970-1915
    EISSN: 0974-0422
  • Source: Open Access: PubMed Central
    Geneva Foundation Free Medical Journals at publisher websites
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