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Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations

International journal of environmental research and public health, 2020-05, Vol.17 (9), p.3326 [Peer Reviewed Journal]

2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 by the authors. 2020 ;ISSN: 1660-4601 ;ISSN: 1661-7827 ;EISSN: 1660-4601 ;DOI: 10.3390/ijerph17093326 ;PMID: 32403261

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  • Title:
    Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations
  • Author: Jing, Jane Lee Jia ; Pei Yi, Thong ; Bose, Rajendran J C ; McCarthy, Jason R ; Tharmalingam, Nagendran ; Madheswaran, Thiagarajan
  • Subjects: Air pollution ; Airborne microorganisms ; Alcohols ; Cleaning compounds ; Coronaviruses ; COVID-19 ; Hygiene ; Personal hygiene ; Review ; Sanitizers ; Side effects ; Soaps ; Viruses
  • Is Part Of: International journal of environmental research and public health, 2020-05, Vol.17 (9), p.3326
  • Description: Hand hygiene is of utmost importance as it may be contaminated easily from direct contact with airborne microorganism droplets from coughs and sneezes. Particularly in situations like pandemic outbreak, it is crucial to interrupt the transmission chain of the virus by the practice of proper hand sanitization. It can be achieved with contact isolation and strict infection control tool like maintaining good hand hygiene in hospital settings and in public. The success of the hand sanitization solely depends on the use of effective hand disinfecting agents formulated in various types and forms such as antimicrobial soaps, water-based or alcohol-based hand sanitizer, with the latter being widely used in hospital settings. To date, most of the effective hand sanitizer products are alcohol-based formulations containing 62%-95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses. This systematic review correlated with the data available in Pubmed, and it will investigate the range of available hand sanitizers and their effectiveness as well as the formulation aspects, adverse effects, and recommendations to enhance the formulation efficiency and safety. Further, this article highlights the efficacy of alcohol-based hand sanitizer against the coronavirus.
  • Publisher: Switzerland: MDPI AG
  • Language: English
  • Identifier: ISSN: 1660-4601
    ISSN: 1661-7827
    EISSN: 1660-4601
    DOI: 10.3390/ijerph17093326
    PMID: 32403261
  • Source: GFMER Free Medical Journals
    PubMed Central
    Coronavirus Research Database
    ProQuest Central
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