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Aspirin intake is not associated with diabetic retinopathy and diabetic macular edema: A report from the Fushun diabetic retinopathy cohort study

Indian journal of ophthalmology, 2024-02, Vol.72 (Suppl 2), p.S298-S302 [Peer Reviewed Journal]

Copyright © 2024 Copyright: © 2024 Indian Journal of Ophthalmology. ;COPYRIGHT 2024 Medknow Publications and Media Pvt. Ltd. ;ISSN: 0301-4738 ;EISSN: 1998-3689 ;DOI: 10.4103/IJO.IJO_2932_23 ;PMID: 38271427

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  • Title:
    Aspirin intake is not associated with diabetic retinopathy and diabetic macular edema: A report from the Fushun diabetic retinopathy cohort study
  • Author: Lin, Wei ; Li, Dong ; Wen, Liang ; Moonasar, Nived ; Wang, Yu ; Lin, Zhong
  • Subjects: Aspirin ; aspirin intake ; Cohort Studies ; Demographic aspects ; Development and progression ; Diabetes Mellitus, Type 2 - complications ; diabetic macular edema ; Diabetic retinopathy ; Diabetic Retinopathy - complications ; Diabetic Retinopathy - diagnosis ; Diabetic Retinopathy - epidemiology ; Diagnosis ; Dosage and administration ; Dropsy ; Edema ; Humans ; incidence ; Macular Edema - diagnosis ; Macular Edema - epidemiology ; Macular Edema - etiology ; Patient outcomes ; prevalence ; Risk Factors
  • Is Part Of: Indian journal of ophthalmology, 2024-02, Vol.72 (Suppl 2), p.S298-S302
  • Description: We aimed to study the effects of aspirin intake for diabetic retinopathy (DR) and diabetic macular edema (DME) in a cohort from northeastern China. Participants in the Fushun Diabetic Retinopathy Cohort Study were enrolled between July 2012 and May 2013. Fundus photographs of six fields were graded according to the modified Airlie House Classification system. The prevalence, incidence, progression, and regression of DR, as well as the prevalence/incidence of DME, were evaluated at baseline and during follow-up examinations after at least 1 year. In total, 1370 patients were enrolled in the study, and 270 (19.7%) were taking aspirin. The prevalence of any DR in participants with and without aspirin intake was 47.4% and 44.9%, respectively (P = 0.46). The incidence of any DR in patients with and without aspirin intake was 9.2% and 8.3%, respectively (P = 0.74). In univariate regression, there was no association between aspirin intake and the prevalence of any DR and DME (odds ratios (OR), 95% confidence intervals (CI): 0.93, 0.68-1.27 and 1.22, 0.79-1.88, respectively). Aspirin intake was not significantly associated with the prevalence and incidence of DME (OR, 95% CI: 1.22, 0.79-1.88 and 1.79, 0.62-5.17, respectively). Furthermore, aspirin intake was not significantly associated with DR progression or regression (OR, 95% CI: 1.04, 0.66-1.66 and 0.75, 0.52-1.09, respectively). Aspirin intake was not associated with the prevalence and incidence of any DR or DME in a northeastern Chinese population. Neither progression nor regression of DR revealed a significant association with aspirin intake.
  • Publisher: India: Medknow Publications and Media Pvt. Ltd
  • Language: English
  • Identifier: ISSN: 0301-4738
    EISSN: 1998-3689
    DOI: 10.4103/IJO.IJO_2932_23
    PMID: 38271427
  • Source: GFMER Free Medical Journals
    MEDLINE
    PubMed Central
    Medknow Open Access Medical Journals
    ProQuest Central
    DOAJ Directory of Open Access Journals
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