skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Rotors and the Dynamics of Cardiac Fibrillation

Circulation research, 2013-03, Vol.112 (5), p.849-862 [Peer Reviewed Journal]

2013 American Heart Association, Inc. ;ISSN: 0009-7330 ;EISSN: 1524-4571 ;DOI: 10.1161/CIRCRESAHA.111.300158 ;PMID: 23449547

Full text available

Citations Cited by
  • Title:
    Rotors and the Dynamics of Cardiac Fibrillation
  • Author: Pandit, Sandeep V ; Jalife, José
  • Subjects: Animals ; Atrial Fibrillation - physiopathology ; Atrial Fibrillation - surgery ; Catheter Ablation ; Electrophysiologic Techniques, Cardiac ; Heart Conduction System - physiopathology ; Humans ; Models, Animal ; Ventricular Fibrillation - physiopathology ; Ventricular Fibrillation - surgery
  • Is Part Of: Circulation research, 2013-03, Vol.112 (5), p.849-862
  • Description: The objective of this article is to present a broad review of the role of cardiac electric rotors and their accompanying spiral waves in the mechanism of cardiac fibrillation. At the outset, we present a brief historical overview regarding reentry and then discuss the basic concepts and terminologies pertaining to rotors and their initiation. Thereafter, the intrinsic properties of rotors and spiral waves, including phase singularities, wavefront curvature, and dominant frequency maps, are discussed. The implications of rotor dynamics for the spatiotemporal organization of fibrillation, independent of the species being studied, are described next. The knowledge gained regarding the role of cardiac structure in the initiation or maintenance of rotors and the ionic bases of spiral waves in the past 2 decades, as well as the significance for drug therapy, is reviewed subsequently. We conclude by examining recent evidence suggesting that rotors are critical in sustaining both atrial and ventricular fibrillation in the human heart and its implications for treatment with radiofrequency ablation.
  • Publisher: United States: American Heart Association, Inc
  • Language: English
  • Identifier: ISSN: 0009-7330
    EISSN: 1524-4571
    DOI: 10.1161/CIRCRESAHA.111.300158
    PMID: 23449547
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    MEDLINE
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait