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Job strain and cardiovascular disease risk factors: meta-analysis of individual-participant data from 47,000 men and women

PloS one, 2013-06, Vol.8 (6), p.e67323 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 Nyberg et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2013 Nyberg et al 2013 Nyberg et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0067323 ;PMID: 23840664

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Title:
Job strain and cardiovascular disease risk factors: meta-analysis of individual-participant data from 47,000 men and women
Author: Nyberg, Solja T ; Fransson, Eleonor I ; Heikkilä, Katriina ; Alfredsson, Lars ; Casini, Annalisa ; Clays, Els ; De Bacquer, Dirk ; Dragano, Nico ; Erbel, Raimund ; Ferrie, Jane E ; Hamer, Mark ; Jöckel, Karl-Heinz ; Kittel, France ; Knutsson, Anders ; Ladwig, Karl-Heinz ; Lunau, Thorsten ; Marmot, Michael G ; Nordin, Maria ; Rugulies, Reiner ; Siegrist, Johannes ; Steptoe, Andrew ; Westerholm, Peter J M ; Westerlund, Hugo ; Theorell, Töres ; Brunner, Eric J ; Singh-Manoux, Archana ; Batty, G David ; Kivimäki, Mika
Testa, Luca
Subjects: Alcohol use ; Alcoholic beverages ; Blood ; Blood lipids ; Blood pressure ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - psychology ; Coronary artery disease ; Coronary heart disease ; Cross-Sectional Studies ; Data processing ; Diabetes mellitus ; Diabetes Mellitus, Type 2 - etiology ; Diabetes Mellitus, Type 2 - psychology ; Female ; Health risk assessment ; Health risks ; Heart ; Heart diseases ; Humans ; Job stress ; Lipids ; Male ; Medical research ; Medicin och hälsovetenskap ; Medicine ; Medicine, Experimental ; Meta-analysis ; Obesity ; Occupational stress ; Odds Ratio ; Physical activity ; Risk analysis ; Risk Factors ; Smoke ; Smoking ; Social and Behavioral Sciences ; Socio-economic aspects ; Socioeconomics ; Stress, Psychological - complications ; Studies ; Work - psychology
Is Part Of: PloS one, 2013-06, Vol.8 (6), p.e67323
Description: Job strain is associated with an increased coronary heart disease risk, but few large-scale studies have examined the relationship of this psychosocial characteristic with the biological risk factors that potentially mediate the job strain - heart disease association. We pooled cross-sectional, individual-level data from eight studies comprising 47,045 participants to investigate the association between job strain and the following cardiovascular disease risk factors: diabetes, blood pressure, pulse pressure, lipid fractions, smoking, alcohol consumption, physical inactivity, obesity, and overall cardiovascular disease risk as indexed by the Framingham Risk Score. In age-, sex-, and socioeconomic status-adjusted analyses, compared to those without job strain, people with job strain were more likely to have diabetes (odds ratio 1.29; 95% CI: 1.11-1.51), to smoke (1.14; 1.08-1.20), to be physically inactive (1.34; 1.26-1.41), and to be obese (1.12; 1.04-1.20). The association between job strain and elevated Framingham risk score (1.13; 1.03-1.25) was attributable to the higher prevalence of diabetes, smoking and physical inactivity among those reporting job strain. In this meta-analysis of work-related stress and cardiovascular disease risk factors, job strain was linked to adverse lifestyle and diabetes. No association was observed between job strain, clinic blood pressure or blood lipids.
Publisher: United States: Public Library of Science
Language: English
Identifier: ISSN: 1932-6203
EISSN: 1932-6203
DOI: 10.1371/journal.pone.0067323
PMID: 23840664
Source: DOAJ : Directory of Open Access Journals
Public Library of Science (PLoS) Journals Open Access
PubMed Central (Open access)
Geneva Foundation Free Medical Journals at publisher websites
AUTh Library subscriptions: ProQuest Central
MEDLINE
SWEPUB Freely available online

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Job strain and cardiovascular disease risk factors: meta-analysis of individual-participant data from 47,000 men and women

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