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Injectable hydrogels for cartilage and bone tissue engineering

Bone research, 2017-05, Vol.5 (2), p.75-94 [Peer Reviewed Journal]

Copyright Nature Publishing Group May 2017 ;Copyright © Wanfang Data Co. Ltd. All Rights Reserved. ;Copyright © 2017 The Author(s) 2017 The Author(s) ;ISSN: 2095-4700 ;EISSN: 2095-6231 ;DOI: 10.1038/boneres.2017.14 ;PMID: 28584674

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  • Title:
    Injectable hydrogels for cartilage and bone tissue engineering
  • Author: Liu, Mei ; Zeng, Xin ; Ma, Chao ; Yi, Huan ; Ali, Zeeshan ; Mou, Xianbo ; Li, Song ; Deng, Yan ; He, Nongyue
  • Subjects: hydrogels; cartilage; engineering ; Review
  • Is Part Of: Bone research, 2017-05, Vol.5 (2), p.75-94
  • Description: Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture scaffolds in cartilage and bone tissue engineering, owing to their high water content, similarity to the natural extracellular matrix (ECM), porous framework for cell transplantation and proliferation, minimal invasive properties, and ability to match irregular defects. In this review, we describe the selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering. In addition, the biology of cartilage and the bony ECM is also summarized. Finally, future perspectives for injectable hydrogels in cartilage and bone tissue engineering are discussed.
  • Publisher: China: Springer Nature B.V
  • Language: Chinese;English
  • Identifier: ISSN: 2095-4700
    EISSN: 2095-6231
    DOI: 10.1038/boneres.2017.14
    PMID: 28584674
  • Source: Open Access: DOAJ Directory of Open Access Journals
    Open Access: PubMed Central
    ProQuest Central

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