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Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations

Circulation (New York, N.Y.), 2016-06, Vol.133 (24), p.2459-2502 [Peer Reviewed Journal]

2016 by the American College of Cardiology Foundation and the American Heart Association, Inc. ;2016 American Heart Association, Inc. ;ISSN: 0009-7322 ;EISSN: 1524-4539 ;DOI: 10.1161/CIRCULATIONAHA.116.022194 ;PMID: 27297342

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  • Title:
    Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations
  • Author: Low Wang, Cecilia C ; Hess, Connie N ; Hiatt, William R ; Goldfine, Allison B
  • Subjects: Atherosclerosis - complications ; Atherosclerosis - drug therapy ; Diabetes Mellitus, Type 2 - complications ; Disease Management ; Heart Failure - complications ; Heart Failure - drug therapy ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use ; Risk Factors
  • Is Part Of: Circulation (New York, N.Y.), 2016-06, Vol.133 (24), p.2459-2502
  • Description: Cardiovascular disease remains the principal cause of death and disability among patients with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying atherosclerosis and heart failure. Unfortunately, these mechanisms are not adequately modulated by therapeutic strategies focusing solely on optimal glycemic control with currently available drugs or approaches. In the setting of multifactorial risk reduction with statins and other lipid-lowering agents, antihypertensive therapies, and antihyperglycemic treatment strategies, cardiovascular complication rates are falling, yet remain higher for patients with diabetes mellitus than for those without. This review considers the mechanisms, history, controversies, new pharmacological agents, and recent evidence for current guidelines for cardiovascular management in the patient with diabetes mellitus to support evidence-based care in the patient with diabetes mellitus and heart disease outside of the acute care setting.
  • Publisher: United States: by the American College of Cardiology Foundation and the American Heart Association, Inc
  • Language: English
  • Identifier: ISSN: 0009-7322
    EISSN: 1524-4539
    DOI: 10.1161/CIRCULATIONAHA.116.022194
    PMID: 27297342
  • Source: GFMER Free Medical Journals
    MEDLINE
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