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Evaluation of enzyme inhibitors in drug discovery: a guide for medicinal chemists and pharmacologists, second edition

ISBN: 111848813X ;ISBN: 9781118540404 ;ISBN: 1118540409 ;ISBN: 9781118488133 ;DOI: 10.1002/9781118540398 ;LCCallNum: QP601.5

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  • Title:
    Evaluation of enzyme inhibitors in drug discovery: a guide for medicinal chemists and pharmacologists, second edition
  • Author: Copeland, Robert A
  • Description: Offers essential guidance for discovering and optimizing novel drug therapies Using detailed examples, Evaluation of Enzyme Inhibitors in Drug Discovery equips researchers with the tools needed to apply the science of enzymology and biochemistry to the discovery, optimization, and preclinical development of drugs that work by inhibiting specific enzyme targets. Readers will applaud this book for its clear and practical presentations, including its expert advice on best practices to follow and pitfalls to avoid. This Second Edition brings the book thoroughly up to date with the latest research findings and practices. Updates explore additional forms of enzyme inhibition and special treatments for enzymes that act on macromolecular substrates. Readers will also find new discussions detailing the development and application of the concept of drug-target residence time. Evaluation of Enzyme Inhibitors in Drug Discovery begins by explaining why enzymes are such important drug targets and then examines enzyme reaction mechanisms. The book covers:
  • Publisher: Hoboken, New Jersey: John Wiley & Sons Inc
  • Creation Date: 2013
  • Format: 572
  • Language: English
  • Identifier: ISBN: 111848813X
    ISBN: 9781118540404
    ISBN: 1118540409
    ISBN: 9781118488133
    DOI: 10.1002/9781118540398
    LCCallNum: QP601.5
  • Source: Ebook Central Academic Complete
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