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Introducing New Vaccines in Developing Countries: Concepts and Approaches to Estimating Burden of Haemophilus influenzae Type b-associated Disease

Journal of health, population and nutrition, 2004-09, Vol.22 (3), p.246-256 [Peer Reviewed Journal]

Copyright © 2004 ICDDR,B: Centre for Health and Population Research ;COPYRIGHT 2004 BioMed Central Ltd. ;Copyright Intenational Centre for Diarrhoeal Disease Research, Bangladesh Sep 2004 ;ISSN: 1606-0997 ;EISSN: 2072-1315 ;PMID: 15609777

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Title:
Introducing New Vaccines in Developing Countries: Concepts and Approaches to Estimating Burden of Haemophilus influenzae Type b-associated Disease
Author: Kilgore, Paul E. ; Nyambat, Batmunkh
Subjects: Bacteria ; Bacterial meningitis ; Child, Preschool ; Children ; Cost of Illness ; Cost-Benefit Analysis ; Developing Countries ; Epidemiologic Studies ; Epidemiology ; Haemophilus Infections - epidemiology ; Haemophilus Infections - mortality ; Haemophilus Infections - prevention & control ; Haemophilus influenzae ; Haemophilus influenzae type b ; Haemophilus influenzae type b - immunology ; Haemophilus Vaccines - administration & dosage ; Health outcomes ; Hemophilus infections ; Humans ; Immunization ; Immunization Programs - organization & administration ; Infant ; LDCs ; Medical research ; Medicine, Experimental ; Meningitis ; Surveillance ; Vaccination ; Vaccines ; Vital Statistics
Is Part Of: Journal of health, population and nutrition, 2004-09, Vol.22 (3), p.246-256
Description: In the past 30 years, great strides have been made in immunizing infants and children routinely in developing countries under the Expanded Programme on Immunization. Despite this, the introduction of Haemophilus influenzae type b (Hib) vaccines has progressed rather slowly compared to previously-introduced vaccines for infant immunizations. This slower uptake has been attributed partly to the need for data on the burden of invasive Hib disease. To understand this need, conceptual underpinnings and prerequisites were explored for Hib disease-burden studies. Methodological approaches were also reviewed for conducting Hib disease-burden studies that may be considered in developing countries. Potential studies span a range of designs that provide varying levels of clinical, laboratory and epidemiologic evidence of the burden of invasive Hib disease. Carefully-conducted studies can lay the foundation for complementary studies of long-term disability due to invasive Hib disease, national economic analysis, and field evaluations of vaccine. Studies done in collaboration with national agencies and clinical investigators will maximize study value and provide critical data for national decision-makers who make choices regarding the introduction of Hib vaccines.
Publisher: Bangladesh: ICDDR,B: Centre for Health and Population Research
Language: English
Identifier: ISSN: 1606-0997
EISSN: 2072-1315
PMID: 15609777
Source: GFMER Free Medical Journals
MEDLINE
Coronavirus Research Database
Bioline International
ProQuest Central

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Introducing New Vaccines in Developing Countries: Concepts and Approaches to Estimating Burden of Haemophilus influenzae Type b-associated Disease

Copyright © 2004 ICDDR,B: Centre for Health and Population Research ;COPYRIGHT 2004 BioMed Central Ltd. ;Copyright Intenational Centre for Diarrhoeal Disease Research, Bangladesh Sep 2004 ;ISSN: 1606-0997 ;EISSN: 2072-1315 ;PMID: 15609777

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