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Effect of treatment with epoetin-β on survival, tumour progression and thromboembolic events in patients with cancer : an updated meta-analysis of 12 randomised controlled studies including 2301 patients

British journal of cancer, 2008-07, Vol.99 (1), p.14-22 [Peer Reviewed Journal]

2008 INIST-CNRS ;Copyright © 2008 Cancer Research UK 2008 Cancer Research UK ;ISSN: 0007-0920 ;EISSN: 1532-1827 ;DOI: 10.1038/sj.bjc.6604408 ;PMID: 18542079 ;CODEN: BJCAAI

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Title:
Effect of treatment with epoetin-β on survival, tumour progression and thromboembolic events in patients with cancer : an updated meta-analysis of 12 randomised controlled studies including 2301 patients
Author: AAPRO, M ; SCHERHAG, A ; BURGER, H. U
Subjects: Adult ; Aged ; Aged, 80 and over ; Anemia - drug therapy ; Anemia - etiology ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Clinical Study ; Disease Progression ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Erythropoietin - adverse effects ; Erythropoietin - therapeutic use ; Female ; Hematinics - adverse effects ; Hematinics - therapeutic use ; Humans ; Male ; Medical sciences ; Middle Aged ; Neoplasms - complications ; Randomized Controlled Trials as Topic ; Recombinant Proteins ; Survival Analysis ; Thromboembolism - etiology ; Tumors
Is Part Of: British journal of cancer, 2008-07, Vol.99 (1), p.14-22
Description: Epoetin-beta is used to treat patients with metastatic cancer undergoing chemotherapy to alleviate the symptoms of anaemia, reduce the risk of blood transfusions and improve quality of life. This meta-analysis of 12 randomised, controlled studies evaluated the impact of epoetin-beta on overall survival, tumour progression and thromboembolic events (TEEs). A total of 2297 patients were included in the analysis (epoetin-beta, n=1244; control, n=1053; 65% solid and 35% nonmyeloid haematological malignancies). A prespecified subgroup analysis assessed the effects in patients with a baseline Hb
Publisher: Basingstoke: Nature Publishing Group
Language: English
Identifier: ISSN: 0007-0920
EISSN: 1532-1827
DOI: 10.1038/sj.bjc.6604408
PMID: 18542079
CODEN: BJCAAI
Source: GFMER Free Medical Journals
MEDLINE
PubMed Central
ProQuest Central

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Effect of treatment with epoetin-β on survival, tumour progression and thromboembolic events in patients with cancer : an updated meta-analysis of 12 randomised controlled studies including 2301 patients

2008 INIST-CNRS ;Copyright © 2008 Cancer Research UK 2008 Cancer Research UK ;ISSN: 0007-0920 ;EISSN: 1532-1827 ;DOI: 10.1038/sj.bjc.6604408 ;PMID: 18542079 ;CODEN: BJCAAI

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