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Angiographically Documented Macular Ischemia after Single Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion

Yonsei Medical Journal, 2017, 58(3), , pp.676-678 [Peer Reviewed Journal]

Copyright: Yonsei University College of Medicine 2017. ;Copyright: Yonsei University College of Medicine 2017 2017 ;ISSN: 0513-5796 ;EISSN: 1976-2437 ;DOI: 10.3349/ymj.2017.58.3.676 ;PMID: 28332380

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Title:
Angiographically Documented Macular Ischemia after Single Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion
Author: Lee, Kyou Ho ; Kang, Eui Chun ; Koh, Hyoung Jun
Subjects: Aged ; Angiogenesis Inhibitors - administration & dosage ; Antibodies, Monoclonal - therapeutic use ; Antibodies, Monoclonal, Humanized - therapeutic use ; Bevacizumab - administration & dosage ; Bevacizumab - adverse effects ; Case Report ; Female ; Fluorescein Angiography ; Humans ; Intravitreal Injections ; Macular Edema - diagnosis ; Macular Edema - drug therapy ; Macular Edema - etiology ; Male ; Middle Aged ; Retina - drug effects ; Retina - pathology ; Retina - physiopathology ; Retinal Vein Occlusion - complications ; Retinal Vein Occlusion - diagnosis ; Retinal Vein Occlusion - drug therapy ; Tomography, Optical Coherence ; Treatment Outcome ; Vascular Endothelial Growth Factor A - immunology ; Visual Acuity - physiology ; Vitreous Body ; 의학일반
Is Part Of: Yonsei Medical Journal, 2017, 58(3), , pp.676-678
Description: This report describes a case of angiographically documented foveal avascular zone (FAZ) enlargement after a single intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO). A 71-year-old female was treated with an intravitreal bevacizumab injection for macular edema following CRVO. Despite successfully decreased edema one month after injection, the postinjection best-corrected visual acuity immediately decreased from 20/40 to 20/1000 (Snellen equivalent). The FAZ area increased from 0.37 mm² to 3.11 mm² (8.4-fold increase). While intravitreal anti-vascular endothelial growth factor is effective and should be considered as a first-line treatment for macular edema secondary to CRVO, it may aggravate macular ischemia.
Publisher: Korea (South): Yonsei University College of Medicine
Language: English
Identifier: ISSN: 0513-5796
EISSN: 1976-2437
DOI: 10.3349/ymj.2017.58.3.676
PMID: 28332380
Source: Geneva Foundation Free Medical Journals
KoreaMed (Open access)
KoreaMed Synapse(OpenAccess)
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PubMed Central
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Angiographically Documented Macular Ischemia after Single Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion

Copyright: Yonsei University College of Medicine 2017. ;Copyright: Yonsei University College of Medicine 2017 2017 ;ISSN: 0513-5796 ;EISSN: 1976-2437 ;DOI: 10.3349/ymj.2017.58.3.676 ;PMID: 28332380

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