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Promoting Kidney Function Recovery in Patients with AKI Requiring RRT

Clinical journal of the American Society of Nephrology, 2015-10, Vol.10 (10), p.1859-1867 [Peer Reviewed Journal]

Copyright © 2015 by the American Society of Nephrology. ;Copyright © 2015 by the American Society of Nephrology 2015 ;ISSN: 1555-9041 ;EISSN: 1555-905X ;DOI: 10.2215/CJN.01170215 ;PMID: 26138260

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Title:
Promoting Kidney Function Recovery in Patients with AKI Requiring RRT
Author: Cerdá, Jorge ; Liu, Kathleen D ; Cruz, Dinna N ; Jaber, Bertrand L ; Koyner, Jay L ; Heung, Michael ; Okusa, Mark D ; Faubel, Sarah
Subjects: Acute Kidney Injury - complications ; Acute Kidney Injury - mortality ; Acute Kidney Injury - physiopathology ; Acute Kidney Injury - therapy ; Anticoagulants - administration & dosage ; Humans ; Kidney Failure, Chronic - epidemiology ; Kidney Failure, Chronic - mortality ; Kidney Failure, Chronic - physiopathology ; Recovery of Function ; Renal Replacement Therapy - methods ; Survival Rate ; Time Factors ; Water-Electrolyte Balance
Is Part Of: Clinical journal of the American Society of Nephrology, 2015-10, Vol.10 (10), p.1859-1867
Description: AKI requiring RRT is associated with high mortality, morbidity, and long-term consequences, including CKD and ESRD. Many patients never recover kidney function; in others, kidney function improves over a period of many weeks or months. Methodologic constraints of the available literature limit our understanding of the recovery process and hamper adequate intervention. Current management strategies have focused on acute care and short-term mortality, but new data indicate that long-term consequences of AKI requiring RRT are substantial. Promotion of kidney function recovery is a neglected focus of research and intervention. This lack of emphasis on recovery is illustrated by the relative paucity of research in this area and by the lack of demonstrated effective management strategies. In this article the epidemiologic implications of kidney recovery after AKI requiring RRT are discussed, the available literature and its methodologic constraints are reviewed, and strategies to improve the understanding of factors that affect kidney function recovery are proposed. Measures to promote kidney function recovery are a serious unmet need, with a great potential to improve short- and long-term patient outcomes.
Publisher: United States: American Society of Nephrology
Language: English
Identifier: ISSN: 1555-9041
EISSN: 1555-905X
DOI: 10.2215/CJN.01170215
PMID: 26138260
Source: PubMed
Geneva Foundation Free Medical Journals at publisher websites
MEDLINE
Alma/SFX Local Collection

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Promoting Kidney Function Recovery in Patients with AKI Requiring RRT

Copyright © 2015 by the American Society of Nephrology. ;Copyright © 2015 by the American Society of Nephrology 2015 ;ISSN: 1555-9041 ;EISSN: 1555-905X ;DOI: 10.2215/CJN.01170215 ;PMID: 26138260

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