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Incidence and risk factors of atrial fibrillation in Asian COPD patients

International journal of chronic obstructive pulmonary disease, 2017-01, Vol.12, p.2523-2530 [Peer Reviewed Journal]

COPYRIGHT 2017 Dove Medical Press Limited ;COPYRIGHT 2017 Dove Medical Press Limited ;2017. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2017 Liao and Chen. This work is published and licensed by Dove Medical Press Limited 2017 ;ISSN: 1178-2005 ;ISSN: 1176-9106 ;EISSN: 1178-2005 ;DOI: 10.2147/COPD.S143691 ;PMID: 28883719

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Title:
Incidence and risk factors of atrial fibrillation in Asian COPD patients
Author: Liao, Kuang-Ming ; Chen, Chung-Yu
Subjects: Adult ; Age ; Aged ; Asian Continental Ancestry Group ; Atrial fibrillation ; Atrial Fibrillation - diagnosis ; Atrial Fibrillation - epidemiology ; Atrial Fibrillation - mortality ; Cardiac arrhythmia ; Cardiovascular disease ; Chronic obstructive lung disease ; Chronic obstructive pulmonary disease ; Clinical medicine ; Comorbidity ; Complications and side effects ; Confidence intervals ; Databases, Factual ; Development and progression ; Diabetes ; Expenditures ; Female ; Gender ; Heart failure ; Heart Failure - epidemiology ; Hospitals ; Humans ; Hypertension ; Hypertension - epidemiology ; Incidence ; Kaplan-Meier Estimate ; Kidney diseases ; Lung diseases, Obstructive ; Male ; Middle Aged ; Original Research ; Population ; Prognosis ; Proportional Hazards Models ; Pulmonary Disease, Chronic Obstructive - diagnosis ; Pulmonary Disease, Chronic Obstructive - epidemiology ; Pulmonary Disease, Chronic Obstructive - mortality ; Retrospective Studies ; Risk Factors ; Stroke ; Taiwan - epidemiology ; Thyroid gland ; Time Factors ; Urbanization
Is Part Of: International journal of chronic obstructive pulmonary disease, 2017-01, Vol.12, p.2523-2530
Description: To investigate the incidence and risk factors of atrial fibrillation (AF) in Asian chronic obstructive pulmonary disease (COPD) patients. We selected a study population older than 40 years with a COPD diagnosis and who had used at least one inhaled bronchodilator medication between 1998 and 2012. The date of the index COPD diagnosis was defined as the index date. We excluded patients with a history of AF, significant mitral valve disease, disorders of the thyroid gland, or ischemic heart disease before the index date. We followed all patients from the index date to the day of AF occurrence, the day of death, or the date of December 31, 2013. The baseline of comorbidities was identified before the index date. Comorbidities included hypertension, diabetes mellitus, end-stage renal disease, congenital heart failure, stroke, peripheral arterial occlusive disease, and malignancy. We included 6,208 COPD patients and 12,409 patients without COPD. The incidence of AF was higher in COPD patients than in those without COPD. The adjusted hazard ratio (HR) for AF among those with COPD was 2.23 with a 95% confidence interval (CI) of 1.98-2.51 compared to those without COPD. After multiple analyses, patients with hypertension (HR 1.43 [95% CI =1.26-1.62]) or heart failure (HR 2.36 [95% CI =1.81-3.08]) were found to have a significantly higher incidence of AF than those without these conditions. It is important for physicians to monitor, prevent, and provide early intervention for AF in COPD patients with hypertension or heart failure.
Publisher: New Zealand: Dove Medical Press Limited
Language: English
Identifier: ISSN: 1178-2005
ISSN: 1176-9106
EISSN: 1178-2005
DOI: 10.2147/COPD.S143691
PMID: 28883719
Source: Open Access: DOAJ Directory of Open Access Journals
GFMER Free Medical Journals
MEDLINE
PubMed Central
ProQuest Central
Dove Press Free

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Incidence and risk factors of atrial fibrillation in Asian COPD patients

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