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Plasmonic Optical Fiber-Grating Immunosensing: A Review

Sensors (Basel, Switzerland), 2017-11, Vol.17 (12), p.2732 [Peer Reviewed Journal]

Copyright MDPI AG 2017 ;2017 by the authors. 2017 ;ISSN: 1424-8220 ;EISSN: 1424-8220 ;DOI: 10.3390/s17122732 ;PMID: 29186871

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  • Title:
    Plasmonic Optical Fiber-Grating Immunosensing: A Review
  • Author: Guo, Tuan ; González-Vila, Álvaro ; Loyez, Médéric ; Caucheteur, Christophe
  • Subjects: Biosensors ; Configurations ; fiber Bragg gratings ; Gratings (spectra) ; Immunosensors ; Interfaces ; Light ; Nanoparticles ; Noble metals ; Optical fibers ; plasmonics ; R&D ; Research & development ; Review ; sensing ; Sensors
  • Is Part Of: Sensors (Basel, Switzerland), 2017-11, Vol.17 (12), p.2732
  • Description: Plasmonic immunosensors are usually made of a noble metal (in the form of a film or nanoparticles) on which bioreceptors are grafted to sense analytes based on the antibody/antigen or other affinity mechanism. Optical fiber configurations are a miniaturized counterpart to the bulky Kretschmann prism and allow easy light injection and remote operation. To excite a surface plasmon (SP), the core-guided light is locally outcoupled. Unclad optical fibers were the first configurations reported to this end. Among the different architectures able to bring light in contact with the surrounding medium, a great quantity of research is today being conducted on metal-coated fiber gratings photo-imprinted in the fiber core, as they provide modal features that enable SP generation at any wavelength, especially in the telecommunication window. They are perfectly suited for use with cost-effective high-resolution interrogators, allowing both a high sensitivity and a low limit of detection to be reached in immunosensing. This paper will review recent progress made in this field with different kinds of gratings: uniform, tilted and eccentric short-period gratings as well as long-period fiber gratings. Practical cases will be reported, showing that such sensors can be used in very small volumes of analytes and even possibly applied to in vivo diagnosis.
  • Publisher: Switzerland: MDPI AG
  • Language: English
  • Identifier: ISSN: 1424-8220
    EISSN: 1424-8220
    DOI: 10.3390/s17122732
    PMID: 29186871
  • Source: PubMed Central (Open access)
    AUTh Library subscriptions: ProQuest Central
    ROAD
    GFMER Free Medical Journals
    DOAJ (Directory of Open Access Journals)
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