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Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

Journal of the American College of Cardiology, 2017-07, Vol.70 (1), p.1-25 [Peer Reviewed Journal]

The Authors ;2017 The Authors ;Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved. ;Copyright Elsevier Limited Jul 4, 2017 ;2017 The Authors 2017 ;ISSN: 0735-1097 ;ISSN: 1558-3597 ;EISSN: 1558-3597 ;DOI: 10.1016/j.jacc.2017.04.052 ;PMID: 28527533

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Title:
Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015
Author: Roth, Gregory A., MD, MPH ; Abajobir, Amanuel, MPH ; Abera, Semaw Ferede, MSc ; Aksut, Baran, MD ; Alam, Tahiya, MPH ; Alam, Khurshid, PhD ; Alla, François, PhD ; Alvis-Guzman, Nelson, PhD ; Amrock, Stephen, MD ; Ärnlöv, Johan, PhD ; Asayesh, Hamid, PhD ; Atey, Tesfay Mehari, MSc ; Avila-Burgos, Leticia, PhD ; Banerjee, Amitava, DPhil ; Barregard, Lars, MD ; Belay Ketema, Ezra, MSc ; Bhutta, Zulfiqar, PhD, MBBS ; Carapetis, Jonathan, MBBS, PhD ; Malta, Deborah Carvalho, MD, PhD ; Castañeda-Orjuela, Carlos Andres, MSc ; Castillo-Rivas, Jacqueline, MPH ; Choi, Jee-Young, PhD ; Christensen, Hanne, DMSCi ; Cirillo, Massimo, MD ; Cooper, Leslie, MD ; Damasceno, Albertino, PhD ; Davletov, Kairat, MD, PhD, MPH ; Dorairaj, Prabhakaran, MD, DM, MSc ; Dubey, Manisha, MPhil ; El Sayed Zaki, Maysaa, MD, PhD ; Faraon, Emerito Jose A., MD ; Farvid, Maryam, PhD ; Feigin, Valery, PhD ; Ding, Eric L., ScD ; Fowkes, Gerry, PhD ; Gebrehiwot, Tsegaye, MPH ; Gillum, Richard, MD ; Gold, Audra, MSc ; Gona, Philimon, PhD ; Hafezi-Nejad, Nima, MD ; Hailu, Tesfaye, MBA ; Hankey, Graeme, MD ; Hassen, Hamid Yimam, MPH ; Hay, Simon I., DSc ; Horino, Masako, MPH ; James, Spencer, MD, MPH ; Javanbakht, Mehdi, PhD ; Karimkhani, Chante, MD ; Kasaeian, Amir, PhD ; Khader, Yousef, ShD ; Khang, Young-Ho, MD ; Khoja, Abdullah T., MBBS, MPH, MBA ; Khubchandani, Jagdish, MBBS, PhD ; Kim, Daniel, DrPH ; Kosen, Soewarta, MD ; Krohn, Kristopher J., BA ; Kwan, Gene, MD ; Lal, Dharmesh Kumar, MD ; Linn, Shai, MD MPH, DrPH ; Malekzadeh, Reza, MD ; Mazidi, Mohsen, PhD ; Meles, Kidanu Gebremariam, MPH ; Mensah, George, MD ; Miller, Ted, PhD ; Mirrakhimov, Erkin, MD ; Mohammed, Shafiu, PhD ; Moran, Andrew E., MD, MPH ; Ngalesoni, Frida, MSc ; Nguyen, Grant, MPH ; Obermeyer, Carla Makhlouf, PhD ; Patton, George, MD ; Pedro, João, MS ; Qato, Dima, PharmD, PhD ; Rahimi, Kazem, DM ; Rai, Rajesh Kumar, MPH ; Ribeiro, Antônio, MD ; Safiri, Saeid, PhD ; Santric Milicevic, Milena, MD, MSc, PhD ; Sartorius, Benn, PhD ; Sepanlou, Sadaf, MD, PhD, MPH ; Shin, Min-Jeong, PhD ; Shishehbor, Mehdi, DO, MPH ; Sobngwi, Eugene, MD, MPhil, PhD ; Stranges, Saverio, MD, PhD ; Swaminathan, Soumya, MD ; Tadele Atnafu, Niguse, MS ; Tesfay, Fisaha, MSc ; Thakur, J.S., MD ; Thrift, Amanda, PhD ; Tyrovolas, Stefanos, PhD ; Vlassov, Vasiliy, MD ; Watkins, David, MD, MPH ; Weintraub, Robert, MBBS ; Werdecker, Andrea, PhD ; Westerman, Ronny, PhD ; Xu, Gelin, PhD ; Yonemoto, Naohiro, MPH ; Yu, Chuanhua, PhD ; Vos, Theo, PhD ; Murray, Christopher, DPhil
Subjects: Adult ; Age ; Aged ; american-heart-association ; Autopsy ; Cardiac and Cardiovascular Systems ; Cardiovascular ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - epidemiology ; Cardiovascular System & Cardiology ; cause of death ; Cause of Death - trends ; cause-specific ; Coronary artery disease ; Death ; deaths ; disability ; Diseases ; Epidemiology ; Fatalities ; Female ; Global Health ; Health risk assessment ; Heart ; Heart diseases ; Humans ; hypertension ; Internal Medicine ; Ischemia ; Kardiologi ; Life expectancy ; Life Expectancy - trends ; Life span ; low-income countries ; Male ; Medicin och hälsovetenskap ; Middle Aged ; Morbidity - trends ; Mortality ; Original Investigation ; peripheral arterial-disease ; Prevalence ; Prospective Studies ; Public health ; Retrospective Studies ; Risk Assessment - methods ; Risk Factors ; Sex Distribution ; Stroke ; Survival Rate - trends ; systematic analysis ; weights ; Young Adult
Is Part Of: Journal of the American College of Cardiology, 2017-07, Vol.70 (1), p.1-25
Description: Abstract Background The burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world. Objectives The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden. Methods CVD mortality was estimated from vital registration and verbal autopsy data. CVD prevalence was estimated using modeling software and data from health surveys, prospective cohorts, health system administrative data, and registries. Years lived with disability (YLD) were estimated by multiplying prevalence by disability weights. Years of life lost (YLL) were estimated by multiplying age-specific CVD deaths by a reference life expectancy. A sociodemographic index (SDI) was created for each location based on income per capita, educational attainment, and fertility. Results In 2015, there were an estimated 422.7 million cases of CVD (95% uncertainty interval: 415.53 to 427.87 million cases) and 17.92 million CVD deaths (95% uncertainty interval: 17.59 to 18.28 million CVD deaths). Declines in the age-standardized CVD death rate occurred between 1990 and 2015 in all high-income and some middle-income countries. Ischemic heart disease was the leading cause of CVD health lost globally, as well as in each world region, followed by stroke. As SDI increased beyond 0.25, the highest CVD mortality shifted from women to men. CVD mortality decreased sharply for both sexes in countries with an SDI >0.75. Conclusions CVDs remain a major cause of health loss for all regions of the world. Sociodemographic change over the past 25 years has been associated with dramatic declines in CVD in regions with very high SDI, but only a gradual decrease or no change in most regions. Future updates of the GBD study can be used to guide policymakers who are focused on reducing the overall burden of noncommunicable disease and achieving specific global health targets for CVD.
Publisher: United States: Elsevier Inc
Language: English
Identifier: ISSN: 0735-1097
ISSN: 1558-3597
EISSN: 1558-3597
DOI: 10.1016/j.jacc.2017.04.052
PMID: 28527533
Source: Freely Accessible Journals
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Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

The Authors ;2017 The Authors ;Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved. ;Copyright Elsevier Limited Jul 4, 2017 ;2017 The Authors 2017 ;ISSN: 0735-1097 ;ISSN: 1558-3597 ;EISSN: 1558-3597 ;DOI: 10.1016/j.jacc.2017.04.052 ;PMID: 28527533

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