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Validation and effect on diabetes control of glycated haemoglobin (HbA1c) point-of-care testing

SAMJ: South African Medical Journal, 2019-02, Vol.109 (2), p.112-115 [Peer Reviewed Journal]

COPYRIGHT 2019 Health & Medical Publishing Group ;This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. ;ISSN: 0256-9574 ;ISSN: 2078-5135 ;EISSN: 2078-5135 ;DOI: 10.7196/SAMJ.2019.v109i2.13447 ;PMID: 30834862

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  • Title:
    Validation and effect on diabetes control of glycated haemoglobin (HbA1c) point-of-care testing
  • Author: Singh, D. ; Pillay, S. ; Pillay, D. ; Aldous, C.M.
  • Subjects: Analysis ; Control ; Decision making ; Developing countries ; Diabetes mellitus ; Diabetes therapy ; Glycosylated hemoglobin ; Health Care Sciences & Services ; Health Policy & Services ; Hemoglobins ; Medical Ethics ; Medical research ; Medical testing products ; Medicine, General & Internal ; Medicine, Legal ; Medicine, Research & Experimental ; Retirement benefits
  • Is Part Of: SAMJ: South African Medical Journal, 2019-02, Vol.109 (2), p.112-115
  • Description: Background. Optimal control of diabetes mellitus (DM) remains daunting globally. Point-of-care testing (POCT) for glycated haemoglobin (HbA1c) enables the clinician to make immediate management decisions and thereby improve DM control and complications. Better control is increasingly being striven for in developing countries where availability of POCT devices is limited.Methods. Every alternate patient who visited the diabetes clinic at Edendale Hospital, Durban, South Africa, between 1 June 2017 and 31 August 2017 was invited to participate in the study. These patients made up the POCT group, with the remainder making up the control laboratory group. The POCT group had Quo-Test HbA1c POCT done at the clinic visit and their treatment was adjusted based on the HbA1c reading, while the control group received standard treatment. The two groups of patients were reviewed at 3 months to identify differences in diabetes control between them.Results. Data from 266 patients were analysed (135 in the POCT group v. 131 in the control group). There was no significant difference between the price of the POCT and laboratory HbA1c tests (p=0.823). The POCT and laboratory HbA1c values showed good correlation at baseline (r=0.995; pConclusions. The Quo-Test HbA1c POCT had good correlation with standard laboratory methods in respect of both glycaemic control and price. Patients who had POCT at baseline showed a significant improvement in glycaemic control at 3 months. HbA1c POCT in the setting of a multifaceted approach to diabetes care has been shown to have definite benefits.
  • Publisher: South Africa: Health and Medical Publishing Group (HMPG)
  • Language: English;Portuguese
  • Identifier: ISSN: 0256-9574
    ISSN: 2078-5135
    EISSN: 2078-5135
    DOI: 10.7196/SAMJ.2019.v109i2.13447
    PMID: 30834862
  • Source: Open Access: African Journals Online
    SciELO
    Geneva Foundation Free Medical Journals at publisher websites
    Sabinet Open Access Journals
    Alma/SFX Local Collection
    DOAJ Directory of Open Access Journals
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