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Retrospective Studies – Utility and Caveats

The Journal of the Royal College of Physicians of Edinburgh, 2020-12, Vol.50 (4), p.398-402 [Peer Reviewed Journal]

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Title:
Retrospective Studies – Utility and Caveats
Author: Talari, Keerthi ; Goyal, Mohit
Is Part Of: The Journal of the Royal College of Physicians of Edinburgh, 2020-12, Vol.50 (4), p.398-402
Description: A thorough understanding of the pros and cons of the various study designs is critical to correct interpretation of their results. Retrospective studies are an important tool to study rare diseases, manifestations and outcomes. Findings of these studies can form the basis on which prospective studies are planned. Retrospective studies however have several limitations owing to their design. Since they depend on review of charts that were originally not designed to collect data for research, some information is bound to be missing. Selection and recall biases also affect the results and reasons for differences in treatment between patients and lost follow ups can often not be ascertained and may lead to bias. Readers need to critically evaluate the methods and carefully interpret the results of retrospective studies before they put them to practice. Researchers should avoid over generalisation of results and be cautious in claiming cause-effect relationship in retrospective studies.
Publisher: London, England: SAGE Publications
Language: English
Identifier: ISSN: 1478-2715
EISSN: 2042-8189
DOI: 10.4997/jrcpe.2020.409
PMID: 33469615
Source: Alma/SFX Local Collection

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