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RADIOALLERGOSORBENT AND INDIRECT FLUORESCENT ANTIBODY TESTS IN IMMUNODIAGNOSIS OF SCHISTOSOMIASIS

The Lancet (British edition), 1978-12, Vol.312 (8102), p.1231-1233 [Peer Reviewed Journal]

1978 ;Copyright Elsevier Limited Dec 9, 1978 ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(78)92102-5

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  • Title:
    RADIOALLERGOSORBENT AND INDIRECT FLUORESCENT ANTIBODY TESTS IN IMMUNODIAGNOSIS OF SCHISTOSOMIASIS
  • Author: Weiss, Niklaus ; Stürchler, Dieter ; Dietrich, FelixM
  • Subjects: Antibodies ; Disease control ; Fluorescence ; Immunodiagnosis ; Immunoglobulin E ; Parasitic diseases ; Patients ; Schistosomiasis ; Wildfowl
  • Is Part Of: The Lancet (British edition), 1978-12, Vol.312 (8102), p.1231-1233
  • Description: Radioallergosorbent tests for specific IgE antibodies to Schistosoma hÅ“matobiumand S. mansoni were positive in 82 and 72%, respectively, of sera from 136 African schistosomiasis patients. 99% of sera from controls (5 free of parasitic disease, 75 infested with hookworm, Ascaris, Trichuris, and/or Onchocerca) were negative. When titres in indirect fluorescent antibody tests were set at the same level of specificity only 38% of patients' sera were positive. A cut-off at a higher concentration increased sensitivity to 65% but lowered specificity (10% controls positive).
  • Publisher: London: Elsevier Ltd
  • Language: English
  • Identifier: ISSN: 0140-6736
    EISSN: 1474-547X
    DOI: 10.1016/S0140-6736(78)92102-5
  • Source: Alma/SFX Local Collection
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