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Negative pressure pulmonary edema after general anesthesia: A case report and literature review

Medicine (Baltimore), 2019-04, Vol.98 (17), p.e15389-e15389 [Peer Reviewed Journal]

Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. 2019 ;ISSN: 0025-7974 ;EISSN: 1536-5964 ;DOI: 10.1097/MD.0000000000015389 ;PMID: 31027133

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  • Title:
    Negative pressure pulmonary edema after general anesthesia: A case report and literature review
  • Author: Liu, Ruizhu ; Wang, Jian ; Zhao, Guoqing ; Su, Zhenbo
  • Subjects: Adult ; Anesthesia, General - adverse effects ; Clinical Case Report ; Diagnosis, Differential ; Endoscopy ; Female ; Humans ; Postoperative Complications - diagnosis ; Pulmonary Edema - diagnosis ; Pulmonary Edema - etiology ; Pulmonary Edema - therapy ; Thyroidectomy
  • Is Part Of: Medicine (Baltimore), 2019-04, Vol.98 (17), p.e15389-e15389
  • Description: Negative pressure pulmonary edema (NPPE) is a dangerous clinical complication and potentially life-threatening emergency without prompt diagnosis and intervention during recovery period after anesthetic extubation. A 25-year-old woman has undergone endoscopic thyroidectomy. After extubation, the patient developed acute respiratory distress with high airway resistance accompanied with wheezing, oxyhemoglobin saturation (SpO2) decreased to 70%. With positive pressure mask ventilation, her condition was stable, SpO2 99%. However, the patient developed pink frothy sputum with diffuse bilateral rales 30 min later after transported to surgical intensive care unit (SICU). Negative pressure pulmonary edema. The patient was undergone assisted ventilation with continuous positive airway pressure (CPAP) and furosemide 20 mg was given intravenously. Postoperative day (POD) 2 her condition became stable, computed tomography (CT) scan indicated the pulmonary edema disappeared. The patient was discharged 6 days later. No abnormalities were observed during following 4 weeks. Although usually the onset of NPPE is rapid, with individual differences NPPE is still challenging. Increased vigilance in monitoring, diagnosis, and treatment are essential to prevent aggravation and further complication.
  • Publisher: United States: Wolters Kluwer Health
  • Language: English
  • Identifier: ISSN: 0025-7974
    EISSN: 1536-5964
    DOI: 10.1097/MD.0000000000015389
    PMID: 31027133
  • Source: IngentaConnect Open Access
    Journals@Ovid Open Access Journal Collection Rolling
    Wolters Kluwer Open Health
    MEDLINE
    PubMed Central
    DOAJ Directory of Open Access Journals
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