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Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening

The New England journal of medicine, 2024-03, Vol.390 (11), p.984-993 [Peer Reviewed Journal]

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Title:
Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening
Author: Imperiale, Thomas F. ; Porter, Kyle ; Zella, Julia ; Gagrat, Zubin D. ; Olson, Marilyn C. ; Statz, Sandi ; Garces, Jorge ; Lavin, Philip T. ; Aguilar, Humberto ; Brinberg, Don ; Berkelhammer, Charles ; Kisiel, John B. ; Limburg, Paul J.
Subjects: Adenoma ; Adult ; Cancer screening ; Clinical Medicine ; Clinical Medicine General ; Colonoscopy ; Colorectal cancer ; Colorectal carcinoma ; Colorectal Neoplasms ; Deoxyribonucleic acid ; DNA ; Early Detection of Cancer ; FDA approval ; Feces ; Gastroenterology ; Gastrointestinal Tract Cancer ; Genetic testing ; Genetics ; Genetics General ; Hematology ; Hemoglobin ; Humans ; Laboratories ; Lesions ; Medical screening ; Oncology ; Outpatient-Based Clinical Medicine ; Paternity ; Population ; Precancerous Conditions ; Prospective Studies ; Sensitivity analysis
Is Part Of: The New England journal of medicine, 2024-03, Vol.390 (11), p.984-993
Description: In adults undergoing screening colonoscopy, a next-generation multitarget stool DNA test had higher sensitivity for colorectal cancer and advanced precancerous lesions than a fecal immunochemical test but lower specificity.
Publisher: United States: Massachusetts Medical Society
Language: English
Identifier: ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMoa2310336
PMID: 38477986
Source: MEDLINE

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