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Efectividad del moxifloxacino intracameral profiláctico para reducir la endoftalmitis posterior a cirugía de cataratas en población chilena

Revista medíca de Chile, 2023-03, Vol.151 (3), p.306-312 [Peer Reviewed Journal]

This work is licensed under a Creative Commons Attribution 4.0 International License. ;ISSN: 0034-9887 ;EISSN: 0717-6163 ;DOI: 10.4067/s0034-98872023000300306

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  • Title:
    Efectividad del moxifloxacino intracameral profiláctico para reducir la endoftalmitis posterior a cirugía de cataratas en población chilena
  • Author: Garretón, Rodolfo ; Liberman, Paulina ; Sanhueza, Camila ; Cruzat, Andrea ; Coria, Marcelo
  • Subjects: MEDICINE, GENERAL & INTERNAL
  • Is Part Of: Revista medíca de Chile, 2023-03, Vol.151 (3), p.306-312
  • Description: Background: Endophthalmitis is a serious infectious complication of cataract surgery, which may lead to vision loss. Aim: To evaluate the effectiveness of intracameral moxifloxacin in reducing endophthalmitis after cataract surgery in Chilean patients. Material and Methods: We reviewed all phacoemulsification surgeries performed between 2012 and 2020 at a public hospital. The use of intraoperative intracameral moxifloxacin and possible surgical complications were recorded. In patients with postoperative endophthalmitis, we reviewed their risk factors and clinical characteristics. Results: In the study, 22,869 phacoemulsification surgeries were registered, with an annual average of 2,541. The use of prophylactic intracameral moxifloxacin started progressively in 2014. In 2018 it was used in 88% of the surgeries. Fifteen eyes evolved with postoperative endophthalmitis, but none of these surgeries used intracameral moxifloxacin. Five and seven cases occurred in 2012 and 2013, respectively. There was a trend favoring moxifloxacin use, as a preventive measure for endophthalmitis, but the difference between groups was not significant (p = 0.56). In the group with endophthalmitis, 33.3% of the eyes were from patients with type 2 diabetes mellitus, in 13.3% there was rupture of the posterior capsule and 60% of the eyes corresponded to female patients. Since 2018 there is no record of endophthalmitis after cataract surgery performed in this center. Conclusions: Intracameral moxifloxacin showed a tendency to reduce the frequency of endophthalmitis after phacoemulsification surgery, but a longer observation period is required to reach statistical significance, due to the low frequency of this complication.
  • Publisher: Sociedad Médica de Santiago
  • Language: Portuguese
  • Identifier: ISSN: 0034-9887
    EISSN: 0717-6163
    DOI: 10.4067/s0034-98872023000300306
  • Source: SciELO
    GFMER Free Medical Journals

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