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Dietary polyphenols as potential nutraceuticals in management of diabetes: a review

Journal of diabetes and metabolic disorders, 2013-08, Vol.12 (1), p.43-43, Article 43 [Peer Reviewed Journal]

Bahadoran et al.; licensee BioMed Central Ltd. 2013 ;COPYRIGHT 2013 BioMed Central Ltd. ;COPYRIGHT 2013 BioMed Central Ltd. ;ISSN: 2251-6581 ;EISSN: 2251-6581 ;DOI: 10.1186/2251-6581-12-43 ;PMID: 23938049

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  • Title:
    Dietary polyphenols as potential nutraceuticals in management of diabetes: a review
  • Author: Bahadoran, Zahra ; Mirmiran, Parvin ; Azizi, Fereidoun
  • Subjects: Adipose tissues ; Care and treatment ; Diabetes ; Diabetes therapy ; Diabetics ; Diet therapy ; Endocrinology ; Health aspects ; Insulin ; Medical research ; Medicine & Public Health ; Medicine, Experimental ; Metabolic Diseases ; Polyphenols ; Review ; Review Article
  • Is Part Of: Journal of diabetes and metabolic disorders, 2013-08, Vol.12 (1), p.43-43, Article 43
  • Description: In recent years, there is growing evidence that plant-foods polyphenols, due to their biological properties, may be unique nutraceuticals and supplementary treatments for various aspects of type 2 diabetes mellitus. In this article we have reviewed the potential efficacies of polyphenols, including phenolic acids, flavonoids, stilbenes, lignans and polymeric lignans, on metabolic disorders and complications induced by diabetes. Based on several in vitro , animal models and some human studies, dietary plant polyphenols and polyphenol-rich products modulate carbohydrate and lipid metabolism, attenuate hyperglycemia, dyslipidemia and insulin resistance, improve adipose tissue metabolism, and alleviate oxidative stress and stress-sensitive signaling pathways and inflammatory processes. Polyphenolic compounds can also prevent the development of long-term diabetes complications including cardiovascular disease, neuropathy, nephropathy and retinopathy. Further investigations as human clinical studies are needed to obtain the optimum dose and duration of supplementation with polyphenolic compounds in diabetic patients.
  • Publisher: London: BioMed Central
  • Language: English
  • Identifier: ISSN: 2251-6581
    EISSN: 2251-6581
    DOI: 10.1186/2251-6581-12-43
    PMID: 23938049
  • Source: PubMed Central
    Alma/SFX Local Collection
    Springer Nature OA/Free Journals
    ProQuest Central
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