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Adherence to Mediterranean diet and health status: meta-analysis

BMJ, 2008-09, Vol.337 (7671), p.673-675 [Peer Reviewed Journal]

Sofi et al 2008 ;Copyright 2008 BMJ Publishing Group Ltd. ;2008 INIST-CNRS ;Copyright BMJ Publishing Group LTD Sep 11, 2008 ;Sofi et al 2008 2008 Sofi et al ;ISSN: 0959-8138 ;ISSN: 0959-8146 ;EISSN: 1468-5833 ;EISSN: 1756-1833 ;DOI: 10.1136/bmj.a1344 ;PMID: 18786971 ;CODEN: BMJOAE

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Title:
Adherence to Mediterranean diet and health status: meta-analysis
Author: Sofi, Francesco ; Cesari, Francesca ; Abbate, Rosanna ; Gensini, Gian Franco ; Casini, Alessandro
Subjects: Alzheimers disease ; Biological and medical sciences ; Cardiovascular diseases ; Cardiovascular Diseases - mortality ; Chronic Disease ; Chronic diseases ; Chronic illnesses ; Cohort Studies ; Confidence interval ; Diet ; Diet, Mediterranean - statistics & numerical data ; Disease risk ; Female ; General aspects ; Health behavior ; Health Status ; Humans ; Incidence ; Male ; Medical research ; Medical sciences ; Mediterranean diet ; Meta-analysis ; Miscellaneous ; Mortality ; Neoplasms - mortality ; Neurodegenerative Diseases - mortality ; Nutrition ; Parkinson disease ; Patient Compliance - statistics & numerical data ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Risk Assessment ; Risk Reduction Behavior
Is Part Of: BMJ, 2008-09, Vol.337 (7671), p.673-675
Description: Objective To systematically review all the prospective cohort studies that have analysed the relation between adherence to a Mediterranean diet, mortality, and incidence of chronic diseases in a primary prevention setting. Design Meta-analysis of prospective cohort studies.Data sources English and non-English publications in PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials from 1966 to 30 June 2008. Studies reviewed Studies that analysed prospectively the association between adherence to a Mediterranean diet, mortality, and incidence of diseases; 12 studies, with a total of 1 574 299 subjects followed for a time ranging from three to 18 years were included.Results The cumulative analysis among eight cohorts (514 816 subjects and 33 576 deaths) evaluating overall mortality in relation to adherence to a Mediterranean diet showed that a two point increase in the adherence score was significantly associated with a reduced risk of mortality (pooled relative risk 0.91, 95% confidence interval 0.89 to 0.94). Likewise, the analyses showed a beneficial role for greater adherence to a Mediterranean diet on cardiovascular mortality (pooled relative risk 0.91, 0.87 to 0.95), incidence of or mortality from cancer (0.94, 0.92 to 0.96), and incidence of Parkinson’s disease and Alzheimer’s disease (0.87, 0.80 to 0.96).Conclusions Greater adherence to a Mediterranean diet is associated with a significant improvement in health status, as seen by a significant reduction in overall mortality (9%), mortality from cardiovascular diseases (9%), incidence of or mortality from cancer (6%), and incidence of Parkinson’s disease and Alzheimer’s disease (13%). These results seem to be clinically relevant for public health, in particular for encouraging a Mediterranean-like dietary pattern for primary prevention of major chronic diseases.
Publisher: London: British Medical Journal Publishing Group
Language: English
Identifier: ISSN: 0959-8138
ISSN: 0959-8146
EISSN: 1468-5833
EISSN: 1756-1833
DOI: 10.1136/bmj.a1344
PMID: 18786971
CODEN: BMJOAE
Source: BMJ Open Access Journals
MEDLINE
Alma/SFX Local Collection
ProQuest Central

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Adherence to Mediterranean diet and health status: meta-analysis

Sofi et al 2008 ;Copyright 2008 BMJ Publishing Group Ltd. ;2008 INIST-CNRS ;Copyright BMJ Publishing Group LTD Sep 11, 2008 ;Sofi et al 2008 2008 Sofi et al ;ISSN: 0959-8138 ;ISSN: 0959-8146 ;EISSN: 1468-5833 ;EISSN: 1756-1833 ;DOI: 10.1136/bmj.a1344 ;PMID: 18786971 ;CODEN: BMJOAE

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