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Endoscopic Ultrasound-Guided Liver Biopsy in Clinical Practice

Gastro hep advances, 2022, Vol.1 (6), p.936-941 [Peer Reviewed Journal]

2022 The Authors ;ISSN: 2772-5723 ;EISSN: 2772-5723 ;DOI: 10.1016/j.gastha.2022.07.007

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  • Title:
    Endoscopic Ultrasound-Guided Liver Biopsy in Clinical Practice
  • Author: Sarkar, Avik ; Dellatore, Peter ; Bhurwal, Abhishek ; Tyberg, Amy ; Shahid, Haroon ; Minacapelli, Carlos D. ; Kahaleh, Michel ; Rustgi, Vinod K. ; Nieto, Jose
  • Subjects: Endoscopic ultrasound-guided liver biopsy ; EUS ; Liver biopsy
  • Is Part Of: Gastro hep advances, 2022, Vol.1 (6), p.936-941
  • Description: Liver biopsies are traditionally performed using percutaneous, transjugular, or surgical approaches. Endoscopic ultrasound (EUS)-guided liver biopsy is a new modality to sample liver parenchyma. This technique allows sampling of both liver lobes and obviates the need for sampling error. However, there is paucity of literature demonstrating that EUS-guided liver biopsy provides adequate tissue sample for histologic analysis. This study aimed to review the experience of 2 large tertiary care centers to demonstrate the efficacy and safety of EUS-guided liver biopsy. All patients undergoing EUS-guided liver biopsy between March 2018 and October 2019 between 2 tertiary care centers were included in this retrospective study. The main outcomes of the study included technical success of EUS-guided liver biopsy, details of the specimen (length of the specimen, number of complete portal tracts), and adverse events of EUS-guided liver biopsy. A total of 229 patients underwent EUS-guided liver biopsy at the 2 tertiary care centers. There was 100% technical success. Of the 229 patients, 226 patients (98.7%) had adequate tissue for histopathological evaluation with a mean total length of 3.20 cm and complete portal tracts of 20.2. Overall, 2.6% of patients had adverse events. Our study illustrates that EUS-guided liver biopsy provides adequate specimen for histologic analysis and is a safe, viable alternative to other methods of liver biopsy.
  • Publisher: Elsevier Inc
  • Language: English
  • Identifier: ISSN: 2772-5723
    EISSN: 2772-5723
    DOI: 10.1016/j.gastha.2022.07.007
  • Source: DOAJ Directory of Open Access Journals
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