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TREATMENT OF CARDIOVASCULAR DISEASE
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Title:
TREATMENT OF CARDIOVASCULAR DISEASE
Author:
MITCHELL, Daniel
;
MATLOCK, Johnathan
;
KHAN, Michael
Subjects:
BEER
;
BIOCHEMISTRY
;
CHEMISTRY
;
COMPOSITIONS THEREOF
;
CULTURE MEDIA
;
ENZYMOLOGY
;
HUMAN NECESSITIES
;
HYGIENE
;
MEDICAL OR VETERINARY SCIENCE
;
METALLURGY
;
MICROBIOLOGY
;
MICROORGANISMS OR ENZYMES
;
MUTATION OR GENETIC ENGINEERING
;
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
;
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
;
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
;
SPIRITS
;
VINEGAR
;
WINE
Description:
This disclosure relates to a nucleic acid comprising a double stranded RNA molecule comprising sense and antisense strands and further comprising a single stranded DNA molecule covalently linked to the 3' end of either the sense or antisense RNA part of the molecule wherein the double stranded inhibitory RNA targets genes associated with cardiovascular disease in the treatment hypercholesterolemia and diseases associated with hypercholesterolemia such as cardiovascular disease. La présente divulgation concerne un acide nucléique comprenant une molécule d'ARN double brin comprenant des brins sens et antisens et comprenant en outre une molécule d'ADN simple brin liée de manière covalente à l'extrémité 3' de la partie ARN sens ou ARN antisens de la molécule, l'ARN inhibiteur double brin ciblant des gènes associés à une maladie cardiovasculaire dans le traitement de l'hypercholestérolémie et de maladies associées à l'hypercholestérolémie telle qu'une maladie cardiovasculaire.
Creation Date:
2022
Language:
English;French
Source:
esp@cenet
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