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Phytosterols, Cholesterol Control, and Cardiovascular Disease

Nutrients, 2021-08, Vol.13 (8), p.2810 [Peer Reviewed Journal]

COPYRIGHT 2021 MDPI AG ;2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 by the authors. 2021 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu13082810 ;PMID: 34444970

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Title:
Phytosterols, Cholesterol Control, and Cardiovascular Disease
Author: Poli, Andrea ; Marangoni, Franca ; Corsini, Alberto ; Manzato, Enzo ; Marrocco, Walter ; Martini, Daniela ; Medea, Gerardo ; Visioli, Francesco
Subjects: Anticholesteremic agents ; Bile ; cardiovascular disease ; Cardiovascular diseases ; Cardiovascular system ; Cholesterol ; Clinical trials ; Dietary supplements ; Disease control ; Food ; Functional foods ; Functional foods & nutraceuticals ; Health risks ; Lipids ; Low density lipoprotein ; Low density lipoproteins ; Medical personnel ; Metabolism ; Natural foods ; Nutrition ; Physicians ; Phytosterols ; plant sterols ; Plasma ; Professionals ; Review ; Sterols ; supplements
Is Part Of: Nutrients, 2021-08, Vol.13 (8), p.2810
Description: The use of phytosterols (or plant sterols) for the control of plasma cholesterol concentrations has recently gained traction because their efficacy is acknowledged by scientific authorities and leading guidelines. Phytosterols, marketed as supplements or functional foods, are formally classified as food in the European Union, are freely available for purchase, and are frequently used without any health professional advice; therefore, they are often self-prescribed, either inappropriately or in situations in which no significant advantage can be obtained. For this reason, a panel of experts with diverse medical and scientific backgrounds was convened by NFI—Nutrition Foundation of Italy—to critically evaluate and summarize the literature available on the topic, with the goal of providing medical doctors and all health professionals useful information to actively govern the use of phytosterols in the context of plasma cholesterol control. Some practical indications to help professionals identify subjects who will most likely benefit from the use of these products, optimizing the therapeutic outcomes, are also provided. The panel concluded that the use of phytosterols as supplements or functional foods to control Low Density Lipoprotein (LDL) cholesterol levels should be preceded by the assessment of some relevant individual characteristics: cardiovascular risk, lipid profile, correct understanding of how to use these products, and willingness to pay for the treatment.
Publisher: Basel: MDPI AG
Language: English
Identifier: ISSN: 2072-6643
EISSN: 2072-6643
DOI: 10.3390/nu13082810
PMID: 34444970
Source: GFMER Free Medical Journals
PubMed Central
ROAD: Directory of Open Access Scholarly Resources
ProQuest Central
DOAJ Directory of Open Access Journals

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Phytosterols, Cholesterol Control, and Cardiovascular Disease

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