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Mean Platelet Volume: A Possible Predictor for Patients with Decompensated Chronic Heart Failure

International journal of general medicine, 2022-01, Vol.15, p.4131-4140 [Peer Reviewed Journal]

2022 Andrei et al. ;COPYRIGHT 2022 Dove Medical Press Limited ;2022 Andrei et al. 2022 Andrei et al. ;ISSN: 1178-7074 ;EISSN: 1178-7074 ;DOI: 10.2147/IJGM.S362257 ;PMID: 35465307

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  • Title:
    Mean Platelet Volume: A Possible Predictor for Patients with Decompensated Chronic Heart Failure
  • Author: Andrei, Cătălina Liliana ; Catană, Andreea ; Sinescu, Crina Julieta ; Mirică, Andreea ; Ceban, Octavian ; Chioncel, Valentin Puiu ; Darabont, Roxana Oana
  • Subjects: 1-year mortality ; 6-month rehospitalization ; Analysis ; Cardiac patients ; Care and treatment ; decompensated heart failure ; Ethylenediaminetetraacetic acid ; Health aspects ; Heart failure ; mean platelet volume ; Medical research ; Medicine, Experimental ; Mortality ; Original Research ; Romania ; Type 2 diabetes
  • Is Part Of: International journal of general medicine, 2022-01, Vol.15, p.4131-4140
  • Description: Despite all medical efforts and discoveries, heart failure (HF) remains one of the most important and common public health problems, with high mortality and hospitalization rates, due to decompensation of HF. In the present study, we aimed to identify a predictive factor through which we can evaluate the risk of readmission and mortality in the first year, given the initial admission of a patient with decompensated heart failure. The parameter we have investigated is the mean platelet volume (MPV). Studies have shown that there is a significant correlation between the value of MPV and the risk of cardiovascular disease (CVD) and cardiovascular (CV) death. In this study, we enrolled 130 patients hospitalized for decompensated chronic HF (NYHA class IV HF or acute pulmonary edema) and analyzed whether there is a relationship between the value of the MPV at admission and 6-month rehospitalization, and 1-year mortality, respectively. The statistical analysis revealed significantly different values (p = 0.041) for MPV at admission between the group of patients without decompensated chronic HF compared to the group of patients with decompensated chronic HF (8.74 fl vs 9.08 fl). Also, the results of our study revealed that patients with decompensated chronic heart failure who were readmitted at 6 months and died at 1 year, respectively, had a higher MPV at admission (>9 fl), compared to those without the above-mentioned events, with a statistical significance. A higher MPV at admission can be considered in our study as an independent predictor for rehospitalization and 1-year mortality of patients with decompensated chronic HF.
  • Publisher: New Zealand: Dove Medical Press Limited
  • Language: English
  • Identifier: ISSN: 1178-7074
    EISSN: 1178-7074
    DOI: 10.2147/IJGM.S362257
    PMID: 35465307
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    PubMed Central
    ROAD: Directory of Open Access Scholarly Resources
    ProQuest Central
    DOAJ Directory of Open Access Journals
    Dove Press Free
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