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Optical coherence tomography angiography findings in patients with branch retinal vein occlusion treated with Anti-VEGF

Arquivos brasileiros de oftalmologia, 2020-03, Vol.83 (2), p.120-126 [Peer Reviewed Journal]

This work is licensed under a Creative Commons Attribution 4.0 International License. ;ISSN: 0004-2749 ;ISSN: 1678-2925 ;EISSN: 1678-2925 ;DOI: 10.5935/0004-2749.20200017 ;PMID: 31778447

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Title:
Optical coherence tomography angiography findings in patients with branch retinal vein occlusion treated with Anti-VEGF
Author: Ciloglu, Emine ; Dogan, Neşe Çetin
Subjects: Aged ; Angiogenesis Inhibitors - therapeutic use ; Capillaries - diagnostic imaging ; Capillaries - drug effects ; Capillaries - pathology ; Female ; Fluorescein Angiography - methods ; Humans ; Macula Lutea - diagnostic imaging ; Macula Lutea - drug effects ; Macula Lutea - pathology ; Macular Edema - diagnostic imaging ; Macular Edema - drug therapy ; Macular Edema - etiology ; Macular Edema - pathology ; Male ; Middle Aged ; OPHTHALMOLOGY ; Reference Values ; Retinal Vein Occlusion - complications ; Retinal Vein Occlusion - diagnostic imaging ; Retinal Vein Occlusion - drug therapy ; Retinal Vein Occlusion - pathology ; Retinal Vessels - diagnostic imaging ; Retinal Vessels - drug effects ; Retinal Vessels - pathology ; Retrospective Studies ; Statistics, Nonparametric ; Time Factors ; Tomography, Optical Coherence - methods ; Treatment Outcome ; Vascular Endothelial Growth Factor A - antagonists & inhibitors ; Visual Acuity
Is Part Of: Arquivos brasileiros de oftalmologia, 2020-03, Vol.83 (2), p.120-126
Description: To investigate retinal microvasculature changes in patients treated with anti-VEGF for macular edema secondary to branch retinal vein occlusion. We examined 38 eyes of 19 patients for the study. We measured superficial and deep capillary plexus vessel densities (%), foveal avascular zone areas (mm2), and central macular thicknesses. Parafoveal superficial and deep capillary plexus values were significantly lower in eyes with branch retinal vein occlusion than in fellow eyes (p<0.001). We found a significant increase in parafoveal deep capillary plexus values after the anti-VEGF treatment (p=0.032). The mean foveal avascular zone was larger in eyes with branch retinal vein occlusion than in control eyes (p<0.001). The mean central macular thickness was significantly higher in eyes with branch retinal vein occlusion than in controls, and we observed a significant decrease in central macular thickness after anti-VEGF treatment (<0.001). In addition, the cystic structures in the deep capillary plexus regressed. Optical coherence tomography angiography enables qualitative and quantitative evaluations during follow-up of patients treated for branch retinal vein occlusion.
Publisher: Brazil: Conselho Brasileiro de Oftalmologia
Language: English;Portuguese
Identifier: ISSN: 0004-2749
ISSN: 1678-2925
EISSN: 1678-2925
DOI: 10.5935/0004-2749.20200017
PMID: 31778447
Source: IngentaConnect Free/Open Access Journals
SciELO
GFMER Free Medical Journals
MEDLINE

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Optical coherence tomography angiography findings in patients with branch retinal vein occlusion treated with Anti-VEGF

This work is licensed under a Creative Commons Attribution 4.0 International License. ;ISSN: 0004-2749 ;ISSN: 1678-2925 ;EISSN: 1678-2925 ;DOI: 10.5935/0004-2749.20200017 ;PMID: 31778447

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