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Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

Bone marrow transplantation (Basingstoke), 2016-06, Vol.51 (6), p.786-792 [Peer Reviewed Journal]

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jun 2016 ;Copyright © 2016 Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 0268-3369 ;EISSN: 1476-5365 ;DOI: 10.1038/bmt.2016.20 ;PMID: 26901709

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Title:
Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually
Author: Passweg, J R ; Baldomero, H ; Bader, P ; Bonini, C ; Cesaro, S ; Dreger, P ; Duarte, R F ; Dufour, C ; Kuball, J ; Farge-Bancel, D ; Gennery, A ; Kröger, N ; Lanza, F ; Nagler, A ; Sureda, A ; Mohty, M
Subjects: Amyloidosis - therapy ; Anemia, Aplastic - therapy ; Cord Blood Stem Cell Transplantation - statistics & numerical data ; Europe ; Fetal blood ; Hematopoietic stem cell transplantation ; Hematopoietic Stem Cell Transplantation - methods ; Hematopoietic Stem Cell Transplantation - statistics & numerical data ; Hematopoietic Stem Cell Transplantation - trends ; Hematopoietic Stem Cell Transplantation - utilization ; Hematopoietic stem cells ; Humans ; Neoplasms - therapy ; Original ; Patient Care Team - statistics & numerical data ; Patient Care Team - trends ; Stem cells ; Surveys and Questionnaires ; Tissue Donors - statistics & numerical data ; Transplantation ; Transplantation, Autologous ; Transplantation, Haploidentical ; Transplantation, Homologous
Is Part Of: Bone marrow transplantation (Basingstoke), 2016-06, Vol.51 (6), p.786-792
Description: A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant activity, more so in Eastern European countries than in the west; a continued increase in the use of haploidentical family donors (by 25%) and slower growth for unrelated donor HSCT. The use of cord blood as a stem cell source has decreased again in 2014. Main indications for HSCT were leukemias: 11 853 (33%; 96% allogeneic); lymphoid neoplasias; 20 802 (57%; 11% allogeneic); solid tumors; 1458 (4%; 3% allogeneic) and non-malignant disorders; 2203 (6%; 88% allogeneic). Changes in transplant activity include more allogeneic HSCT for AML in CR1, myeloproliferative neoplasm (MPN) and aplastic anemia and decreasing use in CLL; and more autologous HSCT for plasma cell disorders and in particular for amyloidosis. In addition, data on numbers of teams doing alternative donor transplants, allogeneic after autologous HSCT, autologous cord blood transplants are presented.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 0268-3369
EISSN: 1476-5365
DOI: 10.1038/bmt.2016.20
PMID: 26901709
Source: Geneva Foundation Free Medical Journals at publisher websites
AUTh Library subscriptions: ProQuest Central
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Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jun 2016 ;Copyright © 2016 Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 0268-3369 ;EISSN: 1476-5365 ;DOI: 10.1038/bmt.2016.20 ;PMID: 26901709

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