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Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): Objectives and Design

American journal of epidemiology, 2012-02, Vol.175 (4), p.315-324 [Peer Reviewed Journal]

American Journal of Epidemiology © The Author 2012. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 2012 ;2015 INIST-CNRS ;Copyright Oxford Publishing Limited(England) Feb 15, 2012 ;ISSN: 0002-9262 ;EISSN: 1476-6256 ;DOI: 10.1093/aje/kwr294 ;PMID: 22234482 ;CODEN: AJEPAS

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Title:
Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): Objectives and Design
Author: Aquino, Estela M. L ; Barreto, Sandhi Maria ; Bensenor, Isabela M ; Carvalho, Marilia S ; Chor, Dóra ; Duncan, Bruce B ; Lotufo, Paulo A ; Mill, José Geraldo ; Molina, Maria Del Carmen ; Mota, Eduardo L. A ; Azeredo Passos, Valéria Maria ; Schmidt, Maria Inês ; Szklo, Moyses
Subjects: Adult ; Aged ; Biological and medical sciences ; Brazil - epidemiology ; Cardiovascular disease ; Cardiovascular Diseases - diagnosis ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - etiology ; Chronic Disease ; Developing Countries ; Diabetes ; Diabetes Mellitus - diagnosis ; Diabetes Mellitus - epidemiology ; Diabetes Mellitus - etiology ; Diabetes. Impaired glucose tolerance ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Epidemiologic Research Design ; Epidemiology ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Female ; General aspects ; Humans ; Incidence ; LDCs ; Longitudinal Studies ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; Obesity - diagnosis ; Obesity - epidemiology ; Obesity - etiology ; Occupational health ; Occupational medicine ; Patient Selection ; Population Surveillance ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Risk ; Sample Size ; Studies
Is Part Of: American journal of epidemiology, 2012-02, Vol.175 (4), p.315-324
Description: Although low- and middle-income countries still bear the burden of major infectious diseases, chronic noncommunicable diseases are becoming increasingly common due to rapid demographic, epidemiologic, and nutritional transitions. However, information is generally scant in these countries regarding chronic disease incidence, social determinants, and risk factors. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute relevant information with respect to the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular diseases and diabetes. In this report, the authors delineate the study's objectives, principal methodological features, and timeline. At baseline, ELSA-Brasil enrolled 15,105 civil servants from 5 universities and 1 research institute. The baseline examination (2008-2010) included detailed interviews, clinical and anthropometric examinations, an oral glucose tolerance test, overnight urine collection, a 12-lead resting electrocardiogram, measurement of carotid intima-media thickness, echocardiography, measurement of pulse wave velocity, hepatic ultrasonography, retinal fundus photography, and an analysis of heart rate variability. Long-term biologic sample storage will allow investigation of biomarkers that may predict cardiovascular diseases and diabetes. Annual telephone surveillance, initiated in 2009, will continue for the duration of the study. A follow-up examination is scheduled for 2012-2013.
Publisher: Cary, NC: Oxford University Press
Language: English
Identifier: ISSN: 0002-9262
EISSN: 1476-6256
DOI: 10.1093/aje/kwr294
PMID: 22234482
CODEN: AJEPAS
Source: GFMER Free Medical Journals
MEDLINE
Alma/SFX Local Collection

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Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): Objectives and Design

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