skip to main content
Guest
My Research
My Account
Sign out
Sign in
This feature requires javascript
Library Search
Find Databases
Browse Search
E-Journals A-Z
E-Books A-Z
Citation Linker
Help
Language:
English
Vietnamese
This feature required javascript
This feature requires javascript
Primo Search
All Library Resources
All
Course Materials
Course Materials
Search For:
Clear Search Box
Search in:
All Library Resources
Or hit Enter to replace search target
Or select another collection:
Search in:
All Library Resources
Search in:
Print Resources
Search in:
Digital Resources
Search in:
Online E-Resources
Advanced Search
Browse Search
This feature requires javascript
Search Limited to:
Search Limited to:
Resource type
criteria input
All items
Books
Articles
Images
Audio Visual
Maps
Graduate theses
Show Results with:
criteria input
that contain my query words
with my exact phrase
starts with
Show Results with:
Search type Index
criteria input
anywhere in the record
in the title
as author/creator
in subject
Full Text
ISBN
ISSN
TOC
Keyword
Field
Show Results with:
in the title
Show Results with:
anywhere in the record
in the title
as author/creator
in subject
Full Text
ISBN
ISSN
TOC
Keyword
Field
This feature requires javascript
The
Cost
of
Control
:
Cost
-effectiveness Analysis of Hybrid Closed-Loop Therapy in Youth
Diabetes care, 2022-09, Vol.45 (9), p.1971-1980
[Peer Reviewed Journal]
Copyright American Diabetes Association Sep 2022 ;ISSN: 0149-5992 ;EISSN: 1935-5548 ;DOI: 10.2337/dc21-2019
Full text available
Citations
Cited by
View Online
Details
Recommendations
Reviews
Times Cited
External Links
This feature requires javascript
Actions
Add to My Research
Remove from My Research
E-mail
Print
Permalink
Citation
EasyBib
EndNote
RefWorks
Delicious
Export RIS
Export BibTeX
This feature requires javascript
Title:
The
Cost
of
Control
:
Cost
-effectiveness Analysis of Hybrid Closed-Loop Therapy in Youth
Author:
Pease, Anthony
;
Callander, Emily
;
Zomer, Ella
;
Abraham, Mary B.
;
Davis, Elizabeth A.
;
Jones, Timothy W.
;
Liew, Danny
;
Zoungas, Sophia
Subjects:
Closed loop systems
;
Cost
analysis
;
Costs
;
Decision analysis
;
Diabetes
;
Diabetes mellitus
;
Diabetes mellitus (insulin dependent)
;
Economic analysis
;
Effectiveness
;
Glucose monitoring
;
Health care
;
Intravenous therapy
;
Markov chains
;
Pediatrics
;
Research design
;
Sensitivity analysis
;
Teenagers
;
Therapy
;
Transition probabilities
;
Young adults
Is Part Of:
Diabetes care, 2022-09, Vol.45 (9), p.1971-1980
Description:
OBJECTIVE Hybrid closed-loop (HCL) therapy is an efficacious management strategy for young people with type 1 diabetes. However, high costs prevent equitable access. We thus sought to evaluate the
cost
-effectiveness of HCL therapy compared with current care among young people with type 1 diabetes in Australia. RESEARCH DESIGN AND METHODS A patient-level Markov model was constructed to simulate disease progression for young people with type 1 diabetes using HCL therapy versus current care, with follow-up from 12 until 25 years of age. Downstream health and economic consequences were compared via decision analysis. Treatment effects and proportions using different technologies to define “current care” were based primarily on data from an Australian pediatric randomized controlled trial. Transition probabilities and utilities for health states were sourced from published studies. Costs were considered from the Australian health care system’s perspective. An annual discount rate of 5% was applied to future costs and outcomes. Uncertainty was evaluated with probabilistic and deterministic sensitivity analyses. RESULTS Use of HCL therapy resulted in an incremental cost-effectiveness ratio of Australian dollars (AUD) $32,789 per quality-adjusted life year (QALY) gained. The majority of simulations (93.3%) were below the commonly accepted willingness-to-pay threshold of AUD $50,000 per QALY gained in Australia. Sensitivity analyses indicated that the base-case results were robust. CONCLUSIONS In this first cost-effectiveness analysis of HCL technologies for the management of young people with type 1 diabetes, HCL therapy was found to be cost-effective compared with current care in Australia.
Publisher:
Alexandria: American Diabetes Association
Language:
English
Identifier:
ISSN: 0149-5992
EISSN: 1935-5548
DOI: 10.2337/dc21-2019
Source:
Geneva Foundation Free Medical Journals at publisher websites
Alma/SFX Local Collection
This feature requires javascript
This feature requires javascript
Back to results list
This feature requires javascript
This feature requires javascript
Searching Remote Databases, Please Wait
Searching for
in
scope:(TDTS),scope:(SFX),scope:(TDT),scope:(SEN),primo_central_multiple_fe
Show me what you have so far
This feature requires javascript
This feature requires javascript