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Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure

Archives of cardiovascular diseases, 2009-03, Vol.102 (3), p.169-175 [Peer Reviewed Journal]

Elsevier Masson SAS ;2009 Elsevier Masson SAS ;2009 INIST-CNRS ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 1875-2136 ;EISSN: 1875-2128 ;DOI: 10.1016/j.acvd.2008.12.006 ;PMID: 19375670

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Title:
Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure
Author: Paulino, Alexandra ; Damy, Thibaud ; Margarit, Laurent ; Stoïca, Maria ; Deswarte, Guillaume ; Khouri, Latifa ; Vermes, Emmanuelle ; Meizels, Anouk ; Hittinger, Luc ; d’Ortho, Marie-Pia
Subjects: Aged ; Atherosclerosis (general aspects, experimental research) ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology and cardiovascular system ; Cardiology. Vascular system ; Cardiovascular ; Congestive heart failure ; Female ; France - epidemiology ; Heart ; Heart Failure - epidemiology ; Heart Failure - physiopathology ; Heart failure, cardiogenic pulmonary edema, cardiac enlargement ; Human health and pathology ; Humans ; Insuffisance cardiaque ; Internal Medicine ; Life Sciences ; Male ; Medical sciences ; Middle Aged ; Pneumology ; Polysomnography ; Prevalence ; Prospective Studies ; Respiratory system : syndromes and miscellaneous diseases ; Risque facteur ; Severity of Illness Index ; Sex Factors ; Sleep Apnea, Central - epidemiology ; Sleep Apnea, Central - physiopathology ; Sleep Apnea, Obstructive - epidemiology ; Sleep Apnea, Obstructive - physiopathology ; Sleep apnoea syndromes ; Stroke Volume ; Syndrome d’apnées du sommeil ; Ventricular Function, Left
Is Part Of: Archives of cardiovascular diseases, 2009-03, Vol.102 (3), p.169-175
Description: Summary Background Heart failure with systolic dysfunction occurs frequently. Studies in North America and Germany have shown a high prevalence of sleep-disordered breathing in patients with heart failure. Aims To assess the prevalence of sleep-disordered breathing and its associated risk factors in French patients with heart failure. Methods A total of 316 patients with stable heart failure and a left ventricular ejection fraction less or equal to 45% underwent polygraphy prospectively to diagnose sleep apnoea syndrome, defined as an apnoea-hypopnoea index greater or equal to 10 events/h. Results Mean age, left ventricular ejection fraction, and body mass index were 59 ± 13 years, 30 ± 11% and 28 ± 6 kg/m2 , respectively. The prevalence of sleep breathing disorder was 81% ( n = 256); 30% of syndromes were classified as central and 70% as obstructive. The mean apnoea-hypopnoea index was high (30 ± 3 events/h) and a large proportion (41%) of syndromes had an apnoea-hypopnoea index greater or equal to 30 events/h. A central sleep apnoea syndrome pattern was associated with more severe heart failure and a more elevated apnoea-hypopnoea index than an obstructive pattern. The prevalence of sleep-disordered breathing was lower in women than in men (64% versus 85%; χ2 = 0.0003) as was its severity (mean apnoea-hypopnoea index 15 ± 13 events/h versus 27 ± 19 events/h, p = 0.0001). Conclusion The prevalence of sleep-disordered breathing was high in a French heart failure population, with most syndromes having an obstructive pattern. Prevalence and severity were higher in men than in women.
Publisher: Amsterdam: Elsevier Masson SAS
Language: English
Identifier: ISSN: 1875-2136
EISSN: 1875-2128
DOI: 10.1016/j.acvd.2008.12.006
PMID: 19375670
Source: Hyper Article en Ligne (HAL) (Open Access)
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Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure

Elsevier Masson SAS ;2009 Elsevier Masson SAS ;2009 INIST-CNRS ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 1875-2136 ;EISSN: 1875-2128 ;DOI: 10.1016/j.acvd.2008.12.006 ;PMID: 19375670

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