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Acute guarana poisoning: report of two cases

Zdravniški vestnik (Ljubljana, Slovenia : 1992), 2018-05, Vol.87 (5-6) [Peer Reviewed Journal]

2018. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1318-0347 ;EISSN: 1581-0024 ;DOI: 10.6016/ZdravVestn.2724

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  • Title:
    Acute guarana poisoning: report of two cases
  • Author: Leben, Lara ; Brvar, Miran
  • Subjects: Caffeine ; Cardiac arrhythmia ; Cardiovascular disease ; Drug overdose ; Poisoning
  • Is Part Of: Zdravniški vestnik (Ljubljana, Slovenia : 1992), 2018-05, Vol.87 (5-6)
  • Description: Guarana (Paullinia cupana) is a South American plant that contains twice more caffeine compared to coffee beans, and has a stimulatory effect. Thus guarana preparations in the form of capsules, tablets, powders, teas, syrups and energy drinks contain a lot of caffeine, which can rapidly cause poisoning even when only slightly overdosed. Caffeine poisoning may result in irritability, insomnia, anxiety, restlessness, muscle twitching, nausea or vomiting, rapid heart beat or cardiac arrhythmias, high blood pressure, sweating, diuresis and gastroinestinal disturbance. This report presents two cases of guarana overdose with the common caffeine poisoning symptoms and signs. Guarana in therapeutic doses can exacerbate underlying cardiac disease (especially cardiac arrhythmias, coronary heart disease, heart failure) and diabetes. Furthermore, children, pregnant and nursing women should avoid guarana as well. Treatment of guarana poisoning is symptomatic, mainly with benzodiazepines and by fluid and electrolyte substitution.
  • Publisher: Ljubljana: ZDRAVNISKI VESTNIK - SLOVENIAN MEDICAL JOURNAL
  • Language: Slovenian
  • Identifier: ISSN: 1318-0347
    EISSN: 1581-0024
    DOI: 10.6016/ZdravVestn.2724
  • Source: DOAJ Directory of Open Access Journals
    AUTh Library subscriptions: ProQuest Central
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