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Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications

Cells (Basel, Switzerland), 2020-02, Vol.9 (3), p.563 [Peer Reviewed Journal]

2020 by the authors. 2020 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells9030563 ;PMID: 32121074

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Title:
Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications
Author: Chu, Dinh-Toi ; Nguyen, Tiep Tien ; Tien, Nguyen Le Bao ; Tran, Dang-Khoa ; Jeong, Jee-Heon ; Anh, Pham Gia ; Thanh, Vo Van ; Truong, Dang Tien ; Dinh, Thien Chu
Subjects: application ; cancer treatment ; Cancer Vaccines - immunology ; Clinical Trials as Topic ; Humans ; mechanisms ; Neoplasms - genetics ; Neoplasms - therapy ; Review ; Risk Factors ; Stem Cell Transplantation - trends ; stem cells ; Stem Cells - cytology
Is Part Of: Cells (Basel, Switzerland), 2020-02, Vol.9 (3), p.563
Description: The insufficient and unspecific target of traditional therapeutic approaches in cancer treatment often leads to therapy resistance and cancer recurrence. Over the past decades, accumulating discoveries about stem cell biology have provided new potential approaches to cure cancer patients. Stem cells possess unique biological actions, including self-renewal, directional migration, differentiation, and modulatory effects on other cells, which can be utilized as regenerative medicine, therapeutic carriers, drug targeting, and generation of immune cells. In this review, we emphasize the mechanisms underlying the use of various types of stem cells in cancer treatment. In addition, we summarize recent progress in the clinical applications of stem cells, as well as common risks of this therapy. We finally give general directions for future studies, aiming to improve overall outcomes in the fight against cancer.
Publisher: Switzerland: MDPI
Language: English
Identifier: ISSN: 2073-4409
EISSN: 2073-4409
DOI: 10.3390/cells9030563
PMID: 32121074
Source: Open Access: DOAJ Directory of Open Access Journals
Open Access: PubMed Central
AUTh Library subscriptions: ProQuest Central
MEDLINE
ROAD: Directory of Open Access Scholarly Resources

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Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications

2020 by the authors. 2020 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells9030563 ;PMID: 32121074

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