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Prevalence and characteristics of fetal alcohol spectrum disorders

Pediatrics (Evanston), 2014-11, Vol.134 (5), p.855-866 [Peer Reviewed Journal]

Copyright © 2014 by the American Academy of Pediatrics. ;Copyright American Academy of Pediatrics Nov 2014 ;Copyright © 2014 by the American Academy of Pediatrics 2014 ;ISSN: 0031-4005 ;EISSN: 1098-4275 ;DOI: 10.1542/peds.2013-3319 ;PMID: 25349310 ;CODEN: PEDIAU

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Title:
Prevalence and characteristics of fetal alcohol spectrum disorders
Author: May, Philip A ; Baete, Amy ; Russo, Jaymi ; Elliott, Amy J ; Blankenship, Jason ; Kalberg, Wendy O ; Buckley, David ; Brooks, Marita ; Hasken, Julie ; Abdul-Rahman, Omar ; Adam, Margaret P ; Robinson, Luther K ; Manning, Melanie ; Hoyme, H Eugene
Subjects: Adult ; Alcohol Drinking - adverse effects ; Alcohol Drinking - epidemiology ; Alcohol Drinking - psychology ; Alcohol use ; Analysis ; Birth defects ; Child ; Child development ; Children ; Effect of alcohol on ; Elementary school students ; Female ; Fetal Alcohol Spectrum Disorders - diagnosis ; Fetal Alcohol Spectrum Disorders - epidemiology ; Fetal alcohol syndrome ; Fetus ; Health aspects ; Humans ; Male ; Maternal Behavior - psychology ; Mothers ; Pregnancy ; Prevalence ; Prevalence studies (Epidemiology) ; Risk factors ; Young Adult
Is Part Of: Pediatrics (Evanston), 2014-11, Vol.134 (5), p.855-866
Description: To determine the prevalence and characteristics of fetal alcohol spectrum disorders (FASD) among first grade students (6- to 7-year-olds) in a representative Midwestern US community. From a consented sample of 70.5% of all first graders enrolled in public and private schools, an oversample of small children (≤ 25th percentile on height, weight, and head circumference) and randomly selected control candidates were examined for physical growth, development, dysmorphology, cognition, and behavior. The children's mothers were interviewed for maternal risk. Total dysmorphology scores differentiate significantly fetal alcohol syndrome (FAS) and partial FAS (PFAS) from one another and from unexposed controls. Alcohol-related neurodevelopmental disorder (ARND) is not as clearly differentiated from controls. Children who had FASD performed, on average, significantly worse on 7 cognitive and behavioral tests and measures. The most predictive maternal risk variables in this community are late recognition of pregnancy, quantity of alcoholic drinks consumed 3 months before pregnancy, and quantity of drinking reported for the index child's father. From the final multidisciplinary case findings, 3 techniques were used to estimate prevalence. FAS in this community likely ranges from 6 to 9 per 1000 children (midpoint, 7.5), PFAS from 11 to 17 per 1000 children (midpoint, 14), and the total rate of FASD is estimated at 24 to 48 per 1000 children, or 2.4% to 4.8% (midpoint, 3.6%). Children who have FASD are more prevalent among first graders in this Midwestern city than predicted by previous, popular estimates.
Publisher: United States: American Academy of Pediatrics
Language: English
Identifier: ISSN: 0031-4005
EISSN: 1098-4275
DOI: 10.1542/peds.2013-3319
PMID: 25349310
CODEN: PEDIAU
Source: MEDLINE
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Prevalence and characteristics of fetal alcohol spectrum disorders

Copyright © 2014 by the American Academy of Pediatrics. ;Copyright American Academy of Pediatrics Nov 2014 ;Copyright © 2014 by the American Academy of Pediatrics 2014 ;ISSN: 0031-4005 ;EISSN: 1098-4275 ;DOI: 10.1542/peds.2013-3319 ;PMID: 25349310 ;CODEN: PEDIAU

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