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The impact of ethnicity on type 2 diabetes

Journal of diabetes and its complications, 2003, Vol.17 (1), p.39-58 [Peer Reviewed Journal]

2003 Elsevier Science Inc. ;2003 INIST-CNRS ;ISSN: 1056-8727 ;EISSN: 1873-460X ;DOI: 10.1016/S1056-8727(02)00190-3 ;PMID: 12505756

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Title:
The impact of ethnicity on type 2 diabetes
Author: Abate, Nicola ; Chandalia, Manisha
Subjects: Adipose Tissue ; Asian Americans ; Biological and medical sciences ; Body Composition ; Continental Population Groups ; Diabetes ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes Mellitus, Type 2 - etiology ; Diabetes Mellitus, Type 2 - prevention & control ; Diabetes Mellitus, Type 2 - therapy ; Diabetes. Impaired glucose tolerance ; Diet ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Ethnic Groups ; Ethnicity ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Exercise ; Female ; Genetic Predisposition to Disease ; Hispanic people ; Humans ; Insulin - metabolism ; Insulin resistance ; Insulin Resistance - genetics ; Insulin Secretion ; Islets of Langerhans - physiopathology ; Life Style ; Lifestyles ; Male ; Medical sciences ; Minority & ethnic groups ; Obesity - complications ; Obesity - etiology ; Obesity - genetics ; Patient education ; Prevention programs ; Public health ; Rural areas ; Socioeconomic Factors ; Type 2 diabetes ; β-cell dysfunction
Is Part Of: Journal of diabetes and its complications, 2003, Vol.17 (1), p.39-58
Description: The rapid increase of diabetes prevalence in the US population and across all westernized world has been associated with environmental changes that promote obesity. Although dietary factors, such as total caloric intake, relative excess of dietary saturated fats content and lack of fibers, together with reduced level of physical activity clearly determine the main features of the “obesogenic” environment typical of “western” societies, the impact of lifestyle factors on obesity and diabetes appears to differ in various ethnic groups. Although ethnic-related differences in lifestyle factors may account for some of the predisposition to obesity and diabetes of various ethnic groups, genetic factors may play a more determinant role. These observations pose important public health questions in regard to strategies for treatment and prevention of diabetes both within the multiethnic US population and in the population of origin of various ethnicities. The elucidation of the pathophysiologic mechanisms responsible for the heterogeneous relationship between obesity and type 2 diabetes in various ethnicities may give important contributions to better understand the complex mechanisms involved in the development of this disease. This review examines epidemiological and pathophysiological aspects of the interaction between environment and ethnic predisposition to type 2 diabetes.
Publisher: New York, NY: Elsevier Inc
Language: English
Identifier: ISSN: 1056-8727
EISSN: 1873-460X
DOI: 10.1016/S1056-8727(02)00190-3
PMID: 12505756
Source: MEDLINE
ProQuest Central

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The impact of ethnicity on type 2 diabetes

2003 Elsevier Science Inc. ;2003 INIST-CNRS ;ISSN: 1056-8727 ;EISSN: 1873-460X ;DOI: 10.1016/S1056-8727(02)00190-3 ;PMID: 12505756

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